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Gene transfer of tumor-reactive TCR confers both high avidity and tumor reactivity to nonreactive peripheral blood mononuclear cells and tumor-infiltrating lymphocytes
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Impact of HLA-B alleles, epitope binding affinity, functional avidity, and viral coinfection on the immunodominance of virus-specific CTL responses
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Telomere length of transferred lymphocytes correlates with in vivo persistence and tumor regression in melanoma patients receiving cell transfer therapy
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Selection of T cell clones expressing high-affinity public TCRs within human cytomegalovirus-specific CD8 T cell responses
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Multiple costimulatory modalities enhance CTL avidity
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Hierarchies in cytokine expression profiles for acute and resolving influenza virus-specific CD8+ T cell responses:: Correlation of cytokine profile and TCR avidity
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Selective growth, in vitro and in vivo, of individual T cell clones from tumor-infiltrating lymphocytes obtained from patients with melanoma
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Activation of resting human primary T cells with chimeric receptors: Costimulation from CD28, inducible costimulator, CD134, and CD137 in series with signals from the TCR zeta chain
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Cutting edge:: predetermined avidity of human CD8 T cells expanded on calibrated MHC/anti-CD28-coated microspheres
S Walter et al.
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Selective induction of high avidity CTL by altering the balance of signals from APC
S Oh et al.
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Antigen density presented by dendritic cells in vivo differentially affects the number and avidity of primary, memory, and recall CD8+ T cells
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Clonal selection, clonal senescence, and clonal succession: The evolution of the T cell response to infection with a persistent virus
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A novel approach to the analysis of specificity, clonality, and frequency of HIV-specific T cell responses reveals a potential mechanism for control of viral escape
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Peptide requirement for CTL activation reflects the sensitivity to CD3 engagement:: Correlation with CD8αβ versus CD8αα expression
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High-avidity CTL exploit two complementary mechanisms to provide better protection against viral infection than low-avidity CTL
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A shift in the phenotype of melan-A-specific CTL identifies melanoma patients with an active tumor-specific immune response
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