Risk factors for automobile accidents caused by falling asleep while driving in obstructive sleep apnea syndrome

Purpose We examined the risk factors for automobile accidents caused by falling asleep while driving in subjects with obstructive sleep apnea syndrome (OSAS). Methods We asked licensed drivers with history of snoring and excessive daytime sleepiness who had undergone polysomnography (PSG) at the Department of Sleep Medicine/Sleep Disorders Center at Aichi Medical University Hospital to complete the questionnaires on accidents caused by falling asleep while driving. As a subjective measure of sleepiness, we used the Epworth sleepiness scale (ESS). Based on PSG results, 2387 subjects diagnosed with OSAS were divided into three groups according to apnea-hypopnea index (AHI): mild-to-moderate (5 a parts per thousand currency signaEuro parts per thousand AHI < 30), severe (30 a parts per thousand currency signaEuro parts per thousand AHI < 60), and very severe (AHI a parts per thousand yenaEuro parts per thousand 60). We performed univariate and multivariate logistic regression on variables that might explain falling asleep at the wheel. Results We compared results between each group and simple snorers (394 subjects with AHI < 5) and found the group with very severe OSAS reported significantly higher rates of driving when drowsy and having accidents in the past 5 years due to falling asleep. Conclusions Our multivariate analysis suggests that scores on the ESS and patient-reported frequency of feeling drowsy while regular driving and working are related to automobile accidents caused by falling asleep while driving.