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Edward W. Harhaj et al.
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Dong-Jun Peng et al.
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Hiroyuki Takahashi et al.
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Macrophage Diversity Enhances Tumor Progression and Metastasis
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Transforming Growth Factor β-activated Kinase 1 (TAK1) Kinase Adaptor, TAK1-binding Protein 2, Plays Dual Roles in TAK1 Signaling by Recruiting Both an Activator and an Inhibitor of TAK1 Kinase in Tumor Necrosis Factor Signaling Pathway
Peter Broglie et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Ubiquitin chain cleavage: CYLD at work
Ramin Massoumi
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Promotion of Lung Carcinogenesis by Chronic Obstructive Pulmonary Disease-Like Airway Inflammation in a K-ras-Induced Mouse Model
Seyed Javad Moghaddam et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2009)
Immunotherapy in Non-Small-Cell Lung Carcinoma: From Inflammation to Vaccination
Michel M. Van den Heuvel et al.
CLINICAL LUNG CANCER (2009)
Bortezomib Plus Gemcitabine/Carboplatin as First-Line Treatment of Advanced Non-small Cell Lung Cancer A Phase II Southwest Oncology Group Study (S0339)
Angela M. Davies et al.
JOURNAL OF THORACIC ONCOLOGY (2009)
Ubiquitylation in innate and adaptive immunity
Vijay G. Bhoj et al.
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Shared principles in NF-κB signaling
Matthew S. Hayden et al.
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Itch: a HECT-type E3 ligase regulating immunity, skin and cancer
G. Melino et al.
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T-Cell receptor-induced NF-κB activation is negatively regulated by E3 ubiquitin ligase Cbl-b
Guilin Qiao et al.
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Cancer-related inflammation
Alberto Mantovani et al.
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The E3 ubiquitin ligase Itch regulates expression of transcription factor Foxp3 and airway inflammation by enhancing the function of transcription factor TIEG1
K. Venuprasad et al.
NATURE IMMUNOLOGY (2008)
The E3 ligase Itch negatively regulates inflammatory signaling pathways by controlling the function of the ubiquitin-editing enzyme A20
Noula Shembade et al.
NATURE IMMUNOLOGY (2008)
Tumor Suppressor CYLD Acts as a Negative Regulator for Non-Typeable Haemophilus influenza-Induced Inflammation in the Middle Ear and Lung of Mice
Jae Hyang Lim et al.
PLOS ONE (2007)
NF-κB is a negative regulator of IL-1β secretion as revealed by genetic and pharmacological inhibition of IKKβ
Florian R. Greten et al.
CELL (2007)
Tumor suppressor CYLD regulates acute lung injury in lethal Streptococcus pneumoniae infections
Jae Hyang Lim et al.
IMMUNITY (2007)
Deubiquitinating enzyme CYLD negatively regulates the ubiquitin-dependent kinase Tak1 and prevents abnormal T cell responses
William W. Reiley et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
The tumor suppressor CYLD regulates entry into mitosis
Frank Stegmeier et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
A cytokine-mediated link between innate immunity, inflammation, and cancer
Wan-Wan Lin et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Pharmacologic inhibition of epigenetic modi. cations, coupled with gene expression profiling, reveals novel targets of aberrant DNA methylation and histone deacetylation in lung cancer
S. Zhong et al.
ONCOGENE (2007)
Protein phosphatase 6 down-regulates TAK1 kinase activation in the IL-1 signaling pathway
Taisuke Kajino et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Impaired regulation of NF-κB and increased susceptibility to colitis-associated tumorigenesis in CYLD-deficient mice
Jun Zhang et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Randomized phase II study of bortezomib alone and bortezomib in combination with docetaxel in previously treated advanced non-small-cell lung cancer
Michael P. Fanucchi et al.
JOURNAL OF CLINICAL ONCOLOGY (2006)
Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-κB signaling
Ramin Massoumi et al.
CELL (2006)
Convergence of itch-induced ubiquitination with MEKK1-JNK signaling in Th2 tolerance and airway inflammation
K Venuprasad et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
The E3 ubiquitin ligase itch couples JNK activation to TNFα-induced cell death by inducing c-FLIPL turnover
LF Chang et al.
CELL (2006)
Posttranscriptional downregulation of c-IAP2 by the ubiquitin protein ligase c-IAP1 in vivo
DB Conze et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins
V Heissmeyer et al.
NATURE IMMUNOLOGY (2004)
NF-κB is essential for induction of CYLD, the negative regulator of NF-κB -: Evidence for a novel inducible autoregulatory feedback pathway
H Jono et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-κB signalling
IE Wertz et al.
NATURE (2004)
Negative regulation of JNK signaling by the tumor suppressor CYLD
W Reiley et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
The IKKNF-kappa B system: A treasure trove for drug development
M Karin et al.
NATURE REVIEWS DRUG DISCOVERY (2004)
Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-κB
TR Brummelkamp et al.
NATURE (2003)
The tumour suppressor CYLD negatively regulates NF-κB signalling by deubiquitination
A Kovalenko et al.
NATURE (2003)
CYLD is a deubiquitinating enzyme that negatively regulates NF-κB activation by TNFR family members
E Trompouki et al.
NATURE (2003)
A resorcylic acid lactone, 5Z-7-oxozeaenol, prevents inflammation by inhibiting the catalytic activity of TAK1 MAPK kinase kinase
J Ninomiya-Tsuji et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Dysregulation of T lymphocyte function in itchy mice: a role for itch in T(H)2 differentiation
DY Fang et al.
NATURE IMMUNOLOGY (2002)
TAK1 is a ubiquitin-dependent kinase of MKK and IKK
C Wang et al.
NATURE (2001)
Interleukin-1 (IL-1) receptor-associated kinase leads to activation of TAK1 by inducing TAB2 translocation in the IL-1 signaling pathway
G Takaesu et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
The MAPK kinase kinase TAK1 plays a central role in coupling the interleukin-1 receptor to both transcriptional and RNA-targeted mechanisms of gene regulation
H Holtmann et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)