期刊
NATURE IMMUNOLOGY
卷 9, 期 9, 页码 953-959出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/ni.f.207
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资金
- Helmut Horten Foundation
- Swiss National Science Foundation
- European Union Sixth Framework Programme (INNOCHEM) [LSHB-CT-2005-518167]
- Swiss State Secretariat for Education and Research
A prominent activity of the chemokine system is the regulation of leukocyte trafficking. Here we summarize recent findings on the initial steps in chemokine receptor-induced signal transduction in leukocytes. In particular, we discuss the potential influences of the formation of oligomers of ligand and receptor and of coupling between chemokine signals and regulators of the cytoskeleton, such as small GTPases.
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