期刊
NATURE IMMUNOLOGY
卷 9, 期 2, 页码 117-118出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/ni0208-117
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Lymphocytes depend on endothelial adhesion molecules such as ICAM-1 and VCAM-1, upregulated with inflammation, to facilitate transmigration across junctional barriers. New data show that ALCAM replaces VCAM-1 in the CNS during the development of neuroinflammatory diseases such as multiple sclerosis.
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