4.8 Article

Genome-wide patterns of genetic variation among elite maize inbred lines

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NATURE GENETICS
卷 42, 期 11, 页码 1027-+

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NATURE PUBLISHING GROUP
DOI: 10.1038/ng.684

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资金

  1. 973 program [2009CB118400, 2007CB815703, 2007CB815705, 2007CB109000]
  2. 863 project [2010AA10A106]
  3. National Natural Science Foundation of China [30725008]
  4. Shenzhen Bureau of Science Technology AMP
  5. Information, China [ZYC200903240077A, CXB200903110066A]
  6. Chinese Academy of Science [GJHZ0701-6]
  7. Danish Natural Science Research Council
  8. US National Science Foundation [DBI-0527192]

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We have resequenced a group of six elite maize inbred lines, including the parents of the most productive commercial hybrid in China. This effort uncovered more than 1,000,000 SNPs, 30,000 indel polymorphisms and 101 low-sequence-diversity chromosomal intervals in the maize genome. We also identified several hundred complete genes that show presence/absence variation among these resequenced lines. We discuss the potential roles of complementation of presence/absence variations and other deleterious mutations in contributing to heterosis. High-density SNP and indel polymorphism markers reported here are expected to be a valuable resource for future genetic studies and the molecular breeding of this important crop.

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