期刊
NATURE GENETICS
卷 41, 期 12, 页码 1275-U29出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/ng.475
关键词
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资金
- Chinese Ministry of Agriculture (948 program)
- Ministry of Science and Technology [2006DFA32140, 2007CB815701, 2007CB815703, 2007CB815705]
- Ministry of Finance [1251610601001]
- National Natural Science Foundation of China [30871707, 30725008]
- Chinese Academy of Agricultural Sciences
- Chinese Academy of Science [GJHZ0701-6, KSCX2-YWN-023]
- US Department of Agriculture
- National Research Initiative [2006-35304-17346]
- National Science Foundation [IOS-07-15513]
- Korea Science and Engineering Foundation-Ministry of Education, Science and Technology [WCU R33-10002, BK21]
- Environmental Biotechnology National Core Research Center [R15-2003-012-01003-0]
- National Research Laboratory [2009-0066339]
- Shenzhen Municipal and Yantian District Governments
- Society of Entrepreneurs Ecology
- Division Of Integrative Organismal Systems
- Direct For Biological Sciences [0715513] Funding Source: National Science Foundation
- Ministry of Education, Science & Technology (MoST), Republic of Korea [R33-2008-000-10002-0] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
- National Research Foundation of Korea [2006-0052330] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
Cucumber is an economically important crop as well as a model system for sex determination studies and plant vascular biology. Here we report the draft genome sequence of Cucumis sativus var. sativus L., assembled using a novel combination of traditional Sanger and next-generation Illumina GA sequencing technologies to obtain 72.2-fold genome coverage. The absence of recent whole-genome duplication, along with the presence of few tandem duplications, explains the small number of genes in the cucumber. Our study establishes that five of the cucumber's seven chromosomes arose from fusions of ten ancestral chromosomes after divergence from Cucumis melo. The sequenced cucumber genome affords insight into traits such as its sex expression, disease resistance, biosynthesis of cucurbitacin and 'fresh green' odor. We also identify 686 gene clusters related to phloem function. The cucumber genome provides a valuable resource for developing elite cultivars and for studying the evolution and function of the plant vascular system.
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