期刊
NATURE GENETICS
卷 41, 期 3, 页码 283-285出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/ng.314
关键词
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资金
- Wellcome Trust
- Deutsche Forschungsgemeinschaft
- German National Genome Research Network
- German Federal Ministry of Education and Research
- State of Bavaria
- European Union [INFSO-RI-031688]
- BHF
- Cardiogenics [LSHM-CT-2006-037593]
- ESRC [ES/G007438/1] Funding Source: UKRI
- Economic and Social Research Council [ES/G007438/1] Funding Source: researchfish
We identify the SLC22A3-LPAL2-LPA gene cluster as a strong susceptibility locus for coronary artery disease (CAD) through a genome-wide haplotype association (GWHA) study. This locus was not identified from previous genome-wide association (GWA) studies focused on univariate analyses of SNPs. The proposed approach may have wide utility for analyzing GWA data for other complex traits.
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