期刊
NATURE GENETICS
卷 40, 期 8, 页码 952-954出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/ng.164
关键词
-
资金
- Howard Hughes Medical Institute Funding Source: Medline
- Medical Research Council [MC_U120097112, MC_U120061454] Funding Source: Medline
- Medical Research Council [MC_U120061454] Funding Source: researchfish
- MRC [MC_U120061454] Funding Source: UKRI
To identify renally expressed genes that influence risk for hypertension, we integrated expression quantitative trait locus (QTL) analysis of the kidney with genome-wide correlation analysis of renal expression profiles and blood pressure in recombinant inbred strains derived from the spontaneously hypertensive rat (SHR). This strategy, together with renal transplantation studies in SHR progenitor, transgenic and congenic strains, identified deficient renal expression of Cd36 encoding fatty acid translocase as a genetically determined risk factor for spontaneous hypertension.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据