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ENZYMATIC C-H BOND ACTIVATION Using push to get pull

期刊

NATURE CHEMISTRY
卷 6, 期 2, 页码 89-91

出版社

NATURE PUBLISHING GROUP
DOI: 10.1038/nchem.1855

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资金

  1. Direct For Mathematical & Physical Scien
  2. Division Of Chemistry [1148597] Funding Source: National Science Foundation
  3. NIGMS NIH HHS [R37 GM036298] Funding Source: Medline

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Cytochrome P450 enzymes are able to oxidize substrates that are more inert than their own surrounding protein framework. Now, a quantitative understanding has emerged as to how the enzymes accomplish this remarkable feat.

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