4.8 Article

Synthesis of 19-substituted geldanamycins with altered conformations and their binding to heat shock protein Hsp90

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Neurosciences

Molecular Chaperones as Rational Drug Targets for Parkinsons Disease Therapeutics

S. K. Kalia et al.

CNS & Neurological Disorders-Drug Targets (2012)

Review Clinical Neurology

Protective Role of Heat Shock Proteins in Parkinson's Disease

Paolo Aridon et al.

NEURODEGENERATIVE DISEASES (2011)

Article Chemistry, Multidisciplinary

Potassium carbonate-silica: a highly effective stationary phase for the chromatographic removal of organotin impurities

David C. Harrowven et al.

CHEMICAL COMMUNICATIONS (2010)

Article Biochemistry & Molecular Biology

Application of Chemoproteomics to Drug Discovery: Identification of a Clinical Candidate Targeting Hsp90

Patrick Fadden et al.

CHEMISTRY & BIOLOGY (2010)

Review Biochemistry & Molecular Biology

Discovery and development of Hsp90 inhibitors: a promising pathway for cancer therapy

James R. Porter et al.

CURRENT OPINION IN CHEMICAL BIOLOGY (2010)

Review Biochemistry & Molecular Biology

Heat Shock Proteins: Therapeutic Drug Targets for Chronic Neurodegeneration?

M. U. Sajjad et al.

CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2010)

Review Pharmacology & Pharmacy

ATPase inhibitors of heat-shock protein 90 second season

Yves L. Janin

DRUG DISCOVERY TODAY (2010)

Review Chemistry, Medicinal

Heat Shock Protein 90: Inhibitors in Clinical Trials

Marco A. Biamonte et al.

JOURNAL OF MEDICINAL CHEMISTRY (2010)

Article Chemistry, Medicinal

ATPases as Drug Targets: Insights from Heat Shock Proteins 70 and 90

Andrew J. Massey

JOURNAL OF MEDICINAL CHEMISTRY (2010)

Review Oncology

Targeting the dynamic HSP90 complex in cancer

Jane Trepel et al.

NATURE REVIEWS CANCER (2010)

Article Oncology

Heat shock proteins in neurodegenerative diseases: Pathogenic roles and therapeutic implications

Hiroaki Adachi et al.

INTERNATIONAL JOURNAL OF HYPERTHERMIA (2009)

Review Chemistry, Multidisciplinary

Design and synthesis of ansamycin antibiotics

Iwona E. Wrona et al.

COMPTES RENDUS CHIMIE (2008)

Article Biochemistry & Molecular Biology

Mechanistic studies on Hsp90 inhibition by ansamycin derivatives

S. C. Onuoha et al.

JOURNAL OF MOLECULAR BIOLOGY (2007)

Article Chemistry, Medicinal

Geldanamycin derivatives and neuroprotective effect on cultured P19-derived neurons

Sarin Tadtong et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2007)

Article Chemistry, Multidisciplinary

Relationship among ligand conformations in solution, in the solid state, and at the Hsp90 binding site: Geldanamycin and radicicol

Pahk Thepchatri et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)

Review Chemistry, Medicinal

Inhibitors of the HSP90 molecular chaperone: Attacking the master regulator in cancer

Edward McDonald et al.

CURRENT TOPICS IN MEDICINAL CHEMISTRY (2006)

Article Biochemistry & Molecular Biology

Geldanamycin induces heat shock protein 70 and protects against MPTP-induced dopaminergic neurotoxicity in mice

HY Shen et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Review Chemistry, Medicinal

Heat shock protein 90 inhibitors. A text book example of medicinal chemistry?

YL Janin

JOURNAL OF MEDICINAL CHEMISTRY (2005)

Article Biochemistry & Molecular Biology

17-AAG, an Hsp90 inhibitor, ameliorates polyglutamine-mediated motor neuron degeneration

M Waza et al.

NATURE MEDICINE (2005)

Article Biochemistry & Molecular Biology

Crystal structure and molecular modeling of 17-DMAG in complex with human Hsp90

JM Jez et al.

CHEMISTRY & BIOLOGY (2003)