期刊
NATURE CHEMISTRY
卷 3, 期 2, 页码 103-113出版社
NATURE PORTFOLIO
DOI: 10.1038/NCHEM.957
关键词
-
资金
- Fannie and John Hertz Foundation
- Scientific Interface from the Burroughs Wellcome Fund
- NSF [0954566]
- Div Of Chem, Bioeng, Env, & Transp Sys
- Directorate For Engineering [0954566] Funding Source: National Science Foundation
The specificity and predictability of Watson-Crick base pairing make DNA a powerful and versatile material for engineering at the nanoscale. This has enabled the construction of a diverse and rapidly growing set of DNA nanostructures and nanodevices through the programmed hybridization of complementary strands. Although it had initially focused on the self-assembly of static structures, DNA nanotechnology is now also becoming increasingly attractive for engineering systems with interesting dynamic properties. Various devices, including circuits, catalytic amplifiers, autonomous molecular motors and reconfigurable nanostructures, have recently been rationally designed to use DNA strand-displacement reactions, in which two strands with partial or full complementarity hybridize, displacing in the process one or more pre-hybridized strands. This mechanism allows for the kinetic control of reaction pathways. Here, we review DNA strand-displacement-based devices, and look at how this relatively simple mechanism can lead to a surprising diversity of dynamic behaviour.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据