4.8 Article

Allosteric inhibition through suppression of transient conformational states

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Multidisciplinary Sciences

Protein activity regulation by conformational entropy

Shiou-Ru Tzeng et al.

NATURE (2012)

Article Biochemistry & Molecular Biology

Evidence for dynamics in proteins as a mechanism for ligand dissociation

Mary J. Carroll et al.

NATURE CHEMICAL BIOLOGY (2012)

Article Multidisciplinary Sciences

Structure of an Intermediate State in Protein Folding and Aggregation

Philipp Neudecker et al.

SCIENCE (2012)

Review Biochemistry & Molecular Biology

Protein dynamics and allostery: an NMR view

Shiou-Ru Tzeng et al.

CURRENT OPINION IN STRUCTURAL BIOLOGY (2011)

Editorial Material Biochemistry & Molecular Biology

Excited-State Control of Protein Activity

Michele Vendruscolo

JOURNAL OF MOLECULAR BIOLOGY (2011)

Article Biochemistry & Molecular Biology

cAMP-Dependent Protein Kinase A Selects the Excited State of the Membrane Substrate Phospholamban

Larry R. Masterson et al.

JOURNAL OF MOLECULAR BIOLOGY (2011)

Article Biochemistry & Molecular Biology

Structural Instability Tuning as a Regulatory Mechanism in Protein-Protein Interactions

Li Chen et al.

MOLECULAR CELL (2011)

Article Multidisciplinary Sciences

Solution structure of a minor and transiently formed state of a T4 lysozyme mutant

Guillaume Bouvignies et al.

NATURE (2011)

Review Biochemistry & Molecular Biology

Allostery in pharmacology: Thermodynamics, evolution and design

Gabor Maksay

PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY (2011)

Article Biochemistry & Molecular Biology

Nanometer Propagation of Millisecond Motions in V-Type Allostery

James M. Lipchock et al.

STRUCTURE (2010)

Review Pharmacology & Pharmacy

In search of negative allosteric modulators of biological targets

Duncan R. Groebe

DRUG DISCOVERY TODAY (2009)

Article Biochemistry & Molecular Biology

TALOS plus : a hybrid method for predicting protein backbone torsion angles from NMR chemical shifts

Yang Shen et al.

JOURNAL OF BIOMOLECULAR NMR (2009)

Article Multidisciplinary Sciences

Dynamic activation of an allosteric regulatory protein

Shiou-Ru Tzeng et al.

NATURE (2009)

Article Biochemistry & Molecular Biology

The role of dynamic conformational ensembles in biomolecular recognition

David D. Boehr et al.

NATURE CHEMICAL BIOLOGY (2009)

Review Biochemistry & Molecular Biology

NMR spectroscopy brings invisible protein states into focus

Andrew J. Baldwin et al.

NATURE CHEMICAL BIOLOGY (2009)

Article Multidisciplinary Sciences

Structural basis for cAMP-mediated allosteric control of the catabolite activator protein

Nataliya Popovych et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Editorial Material Multidisciplinary Sciences

Trapping Moving Targets with Small Molecules

Gregory M. Lee et al.

SCIENCE (2009)

Review Multidisciplinary Sciences

Reaching for high-hanging fruit in drug discovery at protein-protein interfaces

James A. Wells et al.

NATURE (2007)

Article Multidisciplinary Sciences

Intrinsic motions along an enzymatic reaction trajectory

Katherine A. Henzler-Wildman et al.

NATURE (2007)

Article Multidisciplinary Sciences

The mechanism of rate-limiting motions in enzyme function

Eric D. Watt et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Biochemistry & Molecular Biology

1-13C amino acid selective labeling in a 2H15N background for NMR studies of large proteins

Koh Takeuchi et al.

JOURNAL OF BIOMOLECULAR NMR (2007)

Article Multidisciplinary Sciences

Quantitative dynamics and binding studies of the 20S proteasome by NMR

Remco Sprangers et al.

NATURE (2007)

Article Multidisciplinary Sciences

The dynamic energy landscape of dihydrofolate reductase catalysis

David D. Boehr et al.

SCIENCE (2006)

Article Biochemistry & Molecular Biology

Study of highly constitutively active mutants suggests how cAMP activates cAMP receptor protein

H Youn et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Review Biotechnology & Applied Microbiology

Small-molecule inhibitors of protein-protein interactions: Progressing towards the dream

MR Arkin et al.

NATURE REVIEWS DRUG DISCOVERY (2004)

Article Chemistry, Multidisciplinary

Probing slow dynamics in high molecular weight proteins by methyl-TROSY NMR spectroscopy: Application to a 723-residue enzyme

DM Korzhnev et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)

Review Biochemistry & Molecular Biology

Searching for new allosteric sites in enzymes

JA Hardy et al.

CURRENT OPINION IN STRUCTURAL BIOLOGY (2004)

Article Biochemistry & Molecular Biology

FAST-Modelfree: A program for rapid automated analysis of solution NMR spin-relaxation data

R Cole et al.

JOURNAL OF BIOMOLECULAR NMR (2003)

Article Biochemistry & Molecular Biology

Studying excited states of proteins by NMR spectroscopy

FAA Mulder et al.

NATURE STRUCTURAL BIOLOGY (2001)

Article Biochemistry & Molecular Biology

Ligand-induced structural changes to maltodextrin-binding protein as studied by solution NMR spectroscopy

J Evenäs et al.

JOURNAL OF MOLECULAR BIOLOGY (2001)

Article Biochemistry & Molecular Biology

Modeling the cAMP-induced allosteric transition using the crystal structure of CAP-cAMP at 2.1 Å resolution

JM Passner et al.

JOURNAL OF MOLECULAR BIOLOGY (2000)

Article Chemistry, Multidisciplinary

The static magnetic field dependence of chemical exchange linebroadening defines the NMR chemical shift time scale

O Millet et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2000)

Article Biochemistry & Molecular Biology

Efficient analysis of macromolecular rotational diffusion from heteronuclear relaxation data

P Dosset et al.

JOURNAL OF BIOMOLECULAR NMR (2000)