相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。A positive/negative ion-switching, targeted mass spectrometry-based metabolomics platform for bodily fluids, cells, and fresh and fixed tissue
Min Yuan et al.
NATURE PROTOCOLS (2012)
MetaboAnalyst 2.0-a comprehensive server for metabolomic data analysis
Jianguo Xia et al.
NUCLEIC ACIDS RESEARCH (2012)
Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1
Weibo Luo et al.
CELL (2011)
Pyruvate kinase type M2: A key regulator of the metabolic budget system in tumor cells
Sybille Mazurek
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2011)
Acetylation Targets the M2 Isoform of Pyruvate Kinase for Degradation through Chaperone-Mediated Autophagy and Promotes Tumor Growth
Lei Lv et al.
MOLECULAR CELL (2011)
Targeting cancer metabolism: a therapeutic window opens
Matthew G. Vander Heiden
NATURE REVIEWS DRUG DISCOVERY (2011)
Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses
Dimitrios Anastasiou et al.
SCIENCE (2011)
Regulation of cancer cell metabolism
Rob A. Cairns et al.
NATURE REVIEWS CANCER (2011)
Features and development of Coot
P. Emsley et al.
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)
Identification of small molecule inhibitors of pyruvate kinase M2
Matthew G. Vander Heiden et al.
BIOCHEMICAL PHARMACOLOGY (2010)
Evaluation of thieno[3,2-b]pyrrole[3,2-d]pyridazinones as activators of the tumor cell specific M2 isoform of pyruvate kinase
Jian-kang Jiang et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)
Rewiring of glycolysis in cancer cell metabolism
Jason W. Locasale et al.
CELL CYCLE (2010)
Evaluation of Substituted N,N′-Diarylsulfonamides as Activators of the Tumor Cell Specific M2 Isoform of Pyruvate Kinase
Matthew B. Boxer et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism
Cynthia V. Clower et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Evidence for an Alternative Glycolytic Pathway in Rapidly Proliferating Cells
Matthew G. Vander Heiden et al.
SCIENCE (2010)
The Control of the Metabolic Switch in Cancers by Oncogenes and Tumor Suppressor Genes
Arnold J. Levine et al.
SCIENCE (2010)
Targeting metabolic transformation for cancer therapy
Daniel A. Tennant et al.
NATURE REVIEWS CANCER (2010)
Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
Dunyaporn Trachootham et al.
NATURE REVIEWS DRUG DISCOVERY (2009)
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
Matthew G. Vander Heiden et al.
SCIENCE (2009)
Tyrosine Phosphorylation Inhibits PKM2 to Promote the Warburg Effect and Tumor Growth
Taro Hitosugi et al.
SCIENCE SIGNALING (2009)
Pyruvate kinase M2 is a phosphotyrosine-binding protein
Heather R. Christofk et al.
NATURE (2008)
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
Heather R. Christofk et al.
NATURE (2008)
Regulation of cell proliferation by interleukin-3-induced nuclear translocation of pyruvate kinase
Akemi Hoshino et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Nuclear translocation of the tumor marker pyruvate kinase M2 induces programmed cell death
Attila Stetak et al.
CANCER RESEARCH (2007)
HKL-3000:: the integration of data reduction and structure solution -: from diffraction images to an initial model in minutes
Wladek Minor et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2006)
ATP citrate lyase inhibition can suppress tumor cell growth
G Hatzivassiliou et al.
CANCER CELL (2005)
PRODRG:: a tool for high-throughput crystallography of protein-ligand complexes
AW Schüttelkopf et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2004)
MolProbity: structure validation and all-atom contact analysis for nucleic acids and their complexes
IW Davis et al.
NUCLEIC ACIDS RESEARCH (2004)
Dominant negative role of the glutamic acid residue conserved in the pyruvate kinase M1 isozyme in the heterotropic allosteric effect involving fructose-1,6-bisphosphate
Y Ikeda et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
The Protein Data Bank
HM Berman et al.
NUCLEIC ACIDS RESEARCH (2000)