相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Synthetic Lethal Compound Combinations Reveal a Fundamental Connection between Wall Teichoic Acid and Peptidoglycan Biosyntheses in Staphylococcus aureus
Jennifer Campbell et al.
ACS CHEMICAL BIOLOGY (2011)
In Vitro Antimicrobial Activity of Wall Teichoic Acid Biosynthesis Inhibitors against Staphylococcus aureus Isolates
Takashi Suzuki et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2011)
Phenotypic Landscape of a Bacterial Cell
Robert J. Nichols et al.
CELL (2011)
Antagonism of Chemical Genetic Interaction Networks Resensitize MRSA to β-Lactam Antibiotics
Sang Ho Lee et al.
CHEMISTRY & BIOLOGY (2011)
Confronting the Challenges of Natural Product-Based Antifungal Discovery
Terry Roemer et al.
CHEMISTRY & BIOLOGY (2011)
Compound Prioritization Methods Increase Rates of Chemical Probe Discovery in Model Organisms
Iain M. Wallace et al.
CHEMISTRY & BIOLOGY (2011)
How to discover new antibiotics: harvesting the parvome
Julian Davies
CURRENT OPINION IN CHEMICAL BIOLOGY (2011)
Antibiotic adjuvants: multicomponent anti-infective strategies
Lindsay Kalan et al.
EXPERT REVIEWS IN MOLECULAR MEDICINE (2011)
Dosage suppression genetic interaction networks enhance functional wiring diagrams of the cell
Leslie Magtanong et al.
NATURE BIOTECHNOLOGY (2011)
High-frequency transposition for determining antibacterial mode of action
Hao Wang et al.
NATURE CHEMICAL BIOLOGY (2011)
The Origin of the Haitian Cholera Outbreak Strain.
Chen-Shan Chin et al.
NEW ENGLAND JOURNAL OF MEDICINE (2011)
Genomewide Screening for Novel Genetic Variations Associated with Ciprofloxacin Resistance in Bacillus anthracis
Masakuni Serizawa et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2010)
Staphylococcus aureus TargetArray: Comprehensive Differential Essential Gene Expression as a Mechanistic Tool To Profile Antibacterials
H. Howard Xu et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2010)
Antibiotic Sensitivity Profiles Determined with an Escherichia coli Gene Knockout Collection: Generating an Antibiotic Bar Code
Anne Liu et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2010)
Colistin Resistance in Acinetobacter baumannii Is Mediated by Complete Loss of Lipopolysaccharide Production
Jennifer H. Moffatt et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2010)
Development of improved inhibitors of wall teichoic acid biosynthesis with potent activity against Staphylococcus aureus
Kyungae Lee et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)
Wall Teichoic Acid Function, Biosynthesis, and Inhibition
Jonathan G. Swoboda et al.
CHEMBIOCHEM (2010)
Chemical Genomic Approaches to Study Model Microbes
Courtney A. Barker et al.
CHEMISTRY & BIOLOGY (2010)
Chemical Probes of Escherichia coli Uncovered through Chemical-Chemical Interaction Profiling with Compounds of Known Biological Activity
Maya A. Farha et al.
CHEMISTRY & BIOLOGY (2010)
How antibiotics kill bacteria: from targets to networks
Michael A. Kohanski et al.
NATURE REVIEWS MICROBIOLOGY (2010)
Highly-multiplexed barcode sequencing: an efficient method for parallel analysis of pooled samples
Andrew M. Smith et al.
NUCLEIC ACIDS RESEARCH (2010)
A universal TagModule collection for parallel genetic analysis of microorganisms
Julia Oh et al.
NUCLEIC ACIDS RESEARCH (2010)
The Zwitterionic Cell Wall Teichoic Acid of Staphylococcus aureus Provokes Skin Abscesses in Mice by a Novel CD4+T-Cell-Dependent Mechanism
Christopher Weidenmaier et al.
PLOS ONE (2010)
Pathway analysis of Candida albicans survival and virulence determinants in a murine infection model
Jeffrey M. Becker et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Gene Annotation and Drug Target Discovery in Candida albicans with a Tagged Transposon Mutant Collection
Julia Oh et al.
PLOS PATHOGENS (2010)
Discovery of a Small Molecule that Blocks Wall Teichoic Acid Biosynthesis in Staphylococcus aureus
Jonathan G. Swoboda et al.
ACS CHEMICAL BIOLOGY (2009)
Isolation, structure and biological activity of phomafungin, a cyclic lipodepsipeptide from a widespread tropical Phoma sp.
Kithsiri Herath et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2009)
A Staphylococcus aureus Fitness Test Platform for Mechanism-Based Profiling of Antibacterial Compounds
Robert G. K. Donald et al.
CHEMISTRY & BIOLOGY (2009)
Probing Teichoic Acid Genetics with Bioactive Molecules Reveals New Interactions among Diverse Processes in Bacterial Cell Wall Biogenesis
Michael A. D'Elia et al.
CHEMISTRY & BIOLOGY (2009)
Chemical Genetic Identification of Peptidoglycan Inhibitors Potentiating Carbapenem Activity against Methicillin-Resistant Staphylococcus aureus
Joann Huber et al.
CHEMISTRY & BIOLOGY (2009)
Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America
Helen W. Boucher et al.
CLINICAL INFECTIOUS DISEASES (2009)
Quantitative phenotyping via deep barcode sequencing
Andrew M. Smith et al.
GENOME RESEARCH (2009)
Simultaneous assay of every Salmonella Typhi gene using one million transposon mutants
Gemma C. Langridge et al.
GENOME RESEARCH (2009)
Chemical Genetic Profiling and Characterization of Small-molecule Compounds That Affect the Biosynthesis of Unsaturated Fatty Acids in Candida albicans
Deming Xu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Isolation, Structure Elucidation, and Biological Activity of Virgineone from Lachnum virgineum Using the Genome-Wide Candida albicans Fitness Test
John Ondeyka et al.
JOURNAL OF NATURAL PRODUCTS (2009)
Two-Color Cell Array Screen Reveals Interdependent Roles for Histone Chaperones and a Chromatin Boundary Regulator in Histone Gene Repression
Jeffrey Fillingham et al.
MOLECULAR CELL (2009)
Discovery of the parnafungins, antifungal metabolites that inhibit mRNA polyadenylation, from the Fusarium larvarum complex and other Hypocrealean fungi
Gerald F. Bills et al.
MYCOLOGIA (2009)
Chemical genomics in Escherichia coli identifies an inhibitor of bacterial lipoprotein targeting
Ranjana Pathania et al.
NATURE CHEMICAL BIOLOGY (2009)
Tn-seq: high-throughput parallel sequencing for fitness and genetic interaction studies in microorganisms
Tim van Opijnen et al.
NATURE METHODS (2009)
ABC Transporters in Saccharomyces cerevisiae and Their Interactors: New Technology Advances the Biology of the ABCC (MRP) Subfamily
Christian M. Paumi et al.
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2009)
Genetic Architecture of Intrinsic Antibiotic Susceptibility
Hany S. Girgis et al.
PLOS ONE (2009)
Genome Analysis of Multi- and Extensively-Drug-Resistant Tuberculosis from KwaZulu-Natal, South Africa
Thomas R. Ioerger et al.
PLOS ONE (2009)
Are essential genes really essential?
Michael A. D'Elia et al.
TRENDS IN MICROBIOLOGY (2009)
A Genome-Wide Screen for Regulators of TORC1 in Response to Amino Acid Starvation Reveals a Conserved Npr2/3 Complex
Taavi K. Neklesa et al.
PLOS GENETICS (2009)
The role of cellular accumulation in determining sensitivity to platinum-based chemotherapy
Matthew D. Hall et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY (2008)
Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator
Sonia Lain et al.
CANCER CELL (2008)
PAP inhibitor with in vivo efficacy identified by Candida albicans genetic profiling of natural products
Bo Jiang et al.
CHEMISTRY & BIOLOGY (2008)
Renaissance in antibacterial discovery from actinomycetes
Richard H. Baltz
CURRENT OPINION IN PHARMACOLOGY (2008)
Antimicrobial activity of ceftobiprole, a novel anti-methicillin-resistant Staphylococcus aureus cephalosporin, tested against contemporary pathogens:: results from the SENTRY Antimicrobial Surveillance Program (2005-2006)
Thomas R. Fritsche et al.
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE (2008)
Whither antibacterial drug discovery?
Steven J. Projan
DRUG DISCOVERY TODAY (2008)
Genomewide screen for negative regulators of sirtuin activity in Saccharomyces cerevisiae reveals 40 loci and links to metabolism
Ryan M. Raisner et al.
GENETICS (2008)
Determination of antibiotic hypersensitivity among 4,000 single-gene-knockout mutants of Escherichia coli
Cindy Tamae et al.
JOURNAL OF BACTERIOLOGY (2008)
The RNA exosome component hRrp6 is a target for 5-fluorouracil in human cells
Susanne Kammler et al.
MOLECULAR CANCER RESEARCH (2008)
An integrated platform of genomic assays reveals small-molecule bioactivities
Shawn Hoon et al.
NATURE CHEMICAL BIOLOGY (2008)
Teichoic acids and related cell-wall glycopolymers in Gram-positive physiology and host interactions
Christopher Weidenmaier et al.
NATURE REVIEWS MICROBIOLOGY (2008)
The Neglected Intrinsic Resistome of Bacterial Pathogens
Alicia Fajardo et al.
PLOS ONE (2008)
Targeting Vesicle Trafficking: An Important Approach to Cancer Chemotherapy
Paul Wright
Recent Patents on Anti-Cancer Drug Discovery (2008)
The chemical genomic portrait of yeast: Uncovering a phenotype for all genes
Maureen E. Hillenmeyer et al.
SCIENCE (2008)
Yeast chemical genomics and drug discovery: an update
Shawn Hoon et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2008)
Identification of small molecule inhibitors of Pseudomonas aeruginosa exoenzyme S using a yeast phenotypic screen
Anthony Arnoldo et al.
PLOS GENETICS (2008)
Invasive methicillin-resistant Staphylococcus aureus infections in the United States
R. Monina Klevens et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2007)
Mechanism-of-action determination of GMP synthase inhibitors and target validation in Candida albicans and Aspergillus fumigatus
Roberto Rodriguez-Suarez et al.
CHEMISTRY & BIOLOGY (2007)
Why are there still over 1000 uncharacterized yeast genes?
Lourdes Pena-Castillo et al.
GENETICS (2007)
Essential gene identification and drug target prioritization in Aspergillus fumigatus
Wenqi Hu et al.
PLOS PATHOGENS (2007)
Systematic pathway analysis using high-resolution fitness profiling of combinatorial gene deletions
Robert P. St Onge et al.
NATURE GENETICS (2007)
Genome-wide analysis of barcoded Saccharomyces cerevisiae gene-deletion mutants in pooled cultures
Sarah E. Pierce et al.
NATURE PROTOCOLS (2007)
Genome-wide fitness test and mechanism-of-action studies of inhibitory compounds in Candida albicans
Deming Xu et al.
PLOS PATHOGENS (2007)
Drugs for bad bugs: confronting the challenges of antibacterial discovery
David J. Payne et al.
NATURE REVIEWS DRUG DISCOVERY (2007)
Genes involved in intrinsic antibiotic resistance of Acinetobacter baylyi
Maria J. Gomez et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2006)
Exploring the mode-of-action of bioactive compounds by chemical-genetic profiling in yeast
Ainslie B. Parsons et al.
CELL (2006)
Marcel Faber Roundtable: Is our antibiotic pipeline unproductive because of starvation, constipation or lack of inspiration?
Richard H. Baltz
JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY (2006)
Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection
Tomoya Baba et al.
MOLECULAR SYSTEMS BIOLOGY (2006)
Genome-wide requirements for resistance to functionally distinct DNA-damaging agents
W Lee et al.
PLOS GENETICS (2005)
Lack of wall teichoic acids in Staphylococcus aureus leads to reduced interactions with endothelial cells and to attenuated virulence in a rabbit model of endocarditis
C Weidenmaier et al.
JOURNAL OF INFECTIOUS DISEASES (2005)
Characterization of novel Mycobacterium tuberculosis and Mycobacterium smegmatis mutants hypersusceptible to β-lactam antibiotics
AR Flores et al.
JOURNAL OF BACTERIOLOGY (2005)
Analysis of β-1,3-glucan assembly in Saccharomyces cerevisiae using a synthetic interaction network and altered sensitivity to caspofungin
G Lesage et al.
GENETICS (2004)
Role of teichoic acids in Staphylococcus aureus nasal colonization, a major risk factor in nosocomial infections
C Weidenmaier et al.
NATURE MEDICINE (2004)
Chemogenomic profiling: Identifying the functional interactions of small molecules in yeast
G Giaever et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes
PY Lum et al.
CELL (2004)
Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways
AB Parsons et al.
NATURE BIOTECHNOLOGY (2004)
Large-scale essential gene identification in Candida albicans and applications to antifungal drug discovery
T Roemer et al.
MOLECULAR MICROBIOLOGY (2003)
Subcellular localization and activity of multidrug resistance proteins
A Rajagopal et al.
MOLECULAR BIOLOGY OF THE CELL (2003)
The art and design of genetic screens:: Escherichia coli
HA Shuman et al.
NATURE REVIEWS GENETICS (2003)
Exploiting genomics, genetics and chemistry to combat antibiotic resistance
D Hughes
NATURE REVIEWS GENETICS (2003)
Functional profiling of the Saccharomyces cerevisiae genome
G Giaever et al.
NATURE (2002)
Transcriptional response of Saccharomyces cerevisiae to DNA-damaging agents does not identify the genes that protect against these agents
GW Birrell et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)
SD Bentley et al.
NATURE (2002)
Lessons learned from the development of an Abl tyrosine kinase inhibitor for chronic myelogenous leukemia
BJ Druker et al.
JOURNAL OF CLINICAL INVESTIGATION (2000)
分享论文
