期刊
NATURE CHEMICAL BIOLOGY
卷 5, 期 2, 页码 74-75出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nchembio0209-74
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Wnt signals are seemingly ubiquitous in biology, controlling processes as diverse as bristle patterning in flies and tissue regeneration in humans. A new report describes the discovery of small molecules that inhibit Wnt signaling by two unprecedented mechanisms, paving the way for fundamental studies and perhaps improved treatment of colon cancer.
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