相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Rapid identification of reactive cysteine residues for site-specific labeling of antibody-Fabs
Jagath R. Junutula et al.
JOURNAL OF IMMUNOLOGICAL METHODS (2008)
Structural effect of a recombinant monoclonal antibody on hinge region peptide bond hydrolysis
Tao Xiang et al.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2007)
Armed antibodies targeting the mucin repeats of the ovarian cancer antigen, MUC16, are highly efficacious in animal tumor models
Youjun Chen et al.
CANCER RESEARCH (2007)
Engineered antibody-drug conjugates with defined sites and stoichiometries of drug attachment
Charlotte F. McDonagh et al.
PROTEIN ENGINEERING DESIGN & SELECTION (2006)
Potent antitumor activity of an auristatin-conjugated, fully human monoclonal antibody to prostate-specific membrane antigen
DS Ma et al.
CLINICAL CANCER RESEARCH (2006)
Antibody-drug conjugates designed to eradicate tumors with homogeneous and heterogeneous expression of the target antigen
YV Kovtun et al.
CANCER RESEARCH (2006)
CR011, a fully human monoclonal anti body-auristatin E conjugate, for the treatment of melanoma
KF Tse et al.
CLINICAL CANCER RESEARCH (2006)
Enhanced activity of monomethylauristatin F through monoclonal antibody delivery: Effects of linker technology on efficacy and toxicity
SO Doronina et al.
BIOCONJUGATE CHEMISTRY (2006)
Drug-conjugated monoclonal antibodies for the treatment of cancer
JM Lambert
CURRENT OPINION IN PHARMACOLOGY (2005)
Structural characterization of the maytansinoid -: monoclonal antibody immunoconjugate, huN901-DM1, by mass spectrometry
LT Wang et al.
PROTEIN SCIENCE (2005)
Reduction-alkylation strategies for the modification of specific monoclonal antibody disulfides
MMC Sun et al.
BIOCONJUGATE CHEMISTRY (2005)
Upping the ante on antibodies
M Baker
NATURE BIOTECHNOLOGY (2005)
Arming antibodies for cancer therapy
P Polakis
CURRENT OPINION IN PHARMACOLOGY (2005)
Arming antibodies: prospects and challenges for immunoconjugates
AM Wu et al.
NATURE BIOTECHNOLOGY (2005)
Monoclonal antibody therapy of cancer
GP Adams et al.
NATURE BIOTECHNOLOGY (2005)
In vitro and in vivo activity of the maytansinoid immunoconjugate huN901-N2′-deacetyl-N2′-(3-mercapto-1-oxopropyl)-maytansine against CD56+ multiple myeloma cells
P Tassone et al.
CANCER RESEARCH (2004)
A prostate-specific membrane antigen-targeted monoclonal antibody-chemotherapeutic conjugate designed for the treatment of prostate cancer
MD Henry et al.
CANCER RESEARCH (2004)
Effects of drug loading on the antitumor activity of a monoclonal antibody drug conjugate
KJ Hamblett et al.
CLINICAL CANCER RESEARCH (2004)
cAC10-vcMMAE, an anti-CD30-monomethyl auristatin E conjugate with potent and selective antitumor activity
JA Francisco et al.
BLOOD (2003)
Development of potent monoclonal antibody auristatin conjugates for cancer therapy
SO Doronina et al.
NATURE BIOTECHNOLOGY (2003)
Cantuzumab mertansine, a maytansinoid immunoconjugate directed to the CanAg antigen: A phase I, pharmacokinetic, and biologic correlative study
AW Tolcher et al.
JOURNAL OF CLINICAL ONCOLOGY (2003)
Cathepsin B-labile dipeptide linkers for lysosomal release of doxorubicin from internalizing immunoconjugates: Model studies of enzymatic drug release and antigen-specific in vitro anticancer activity
GM Dubowchik et al.
BIOCONJUGATE CHEMISTRY (2002)
Site-specific conjugation on serine → cysteine variant monoclonal antibodies
JB Stimmel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)