相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。3.3 Å structure of Niemann-Pick C1 protein reveals insights into the function of the C-terminal luminal domain in cholesterol transport
Xiaochun Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Conformational Changes of CFTR upon Phosphorylation and ATP Binding
Zhe Zhang et al.
CELL (2017)
Activities of the Cytoplasmic Domains of Patched-1 Modulate but Are Not Essential for the Regulation of Canonical Hedgehog Signaling
Andrew Fleet et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Mechanism of inhibition of the tumor suppressor Patched by Sonic Hedgehog
Hanna Tukachinsky et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Structure of human Niemann-Pick C1 protein
Xiaochun Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Alignment of cryo-EM movies of individual particles by optimization of image translations
John L. Rubinstein et al.
JOURNAL OF STRUCTURAL BIOLOGY (2015)
CTFFIND4: Fast and accurate defocus estimation from electron micrographs
Alexis Rohou et al.
JOURNAL OF STRUCTURAL BIOLOGY (2015)
Regulation of the oncoprotein Smoothened by small molecules
Hayley J. Sharpe et al.
NATURE CHEMICAL BIOLOGY (2015)
Identification of a Family of Fatty-Acid-Speciated Sonic Hedgehog Proteins, Whose Members Display Differential Biological Properties
Jun Long et al.
CELL REPORTS (2015)
Measuring the optimal exposure for single particle cryo-EM using a 2.6 Å reconstruction of rotavirus VP6
Timothy Grant et al.
ELIFE (2015)
Tools for macromolecular model building and refinement into electron cryo-microscopy reconstructions
Alan Brown et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2015)
Inhibitors of Hedgehog acyltransferase block Sonic Hedgehog signaling
Elissaveta Petrova et al.
NATURE CHEMICAL BIOLOGY (2013)
The mechanisms of Hedgehog signalling and its roles in development and disease
James Briscoe et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2013)
RELION: Implementation of a Bayesian approach to cryo-EM structure determination
Sjors H. W. Scheres
JOURNAL OF STRUCTURAL BIOLOGY (2012)
Boc and Gas1 Each Form Distinct Shh Receptor Complexes with Ptch1 and Are Required for Shh-Mediated Cell Proliferation
Luisa Izzi et al.
DEVELOPMENTAL CELL (2011)
Overlapping Roles and Collective Requirement for the Coreceptors GAS1, CDO, and BOC in SHH Pathway Function
Benjamin L. Allen et al.
DEVELOPMENTAL CELL (2011)
MolProbity: all-atom structure validation for macromolecular crystallography
Vincent B. Chen et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2010)
Features and development of Coot
P. Emsley et al.
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)
PHENIX: a comprehensive Python-based system for macromolecular structure solution
Paul D. Adams et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2010)
Interactions between Hedgehog proteins and their binding partners come into view
Philip A. Beachy et al.
GENES & DEVELOPMENT (2010)
Hedgehog Signaling in Development and Cancer
Jin Jiang et al.
DEVELOPMENTAL CELL (2008)
The mode of Hedgehog binding to Ihog homologues is not conserved across different phyla
Jason S. McLellan et al.
NATURE (2008)
Bsoft: Image processing and molecular modeling for electron microscopy
J. Bernard Heymann et al.
JOURNAL OF STRUCTURAL BIOLOGY (2007)
Targeting the Hedgehog pathway in cancer
Lee L. Rubin et al.
NATURE REVIEWS DRUG DISCOVERY (2006)
The C-terminal tail of the Hedgehog receptor Patched regulates both localization and turnover
Xingwu Lu et al.
GENES & DEVELOPMENT (2006)
The ihog cell-surface proteins bind hedgehog and mediate pathway activation
SQ Yao et al.
CELL (2006)
Protein sensors for membrane sterols
JL Goldstein et al.
CELL (2006)
Communicating with Hedgehogs
JE Hooper et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)
UCSF chimera - A visualization system for exploratory research and analysis
EF Pettersen et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2004)
Patched acts catalytically to suppress the activity of Smoothened
J Taipale et al.
NATURE (2002)
Hedgehog signaling in animal development: paradigms and principles
PW Ingham et al.
GENES & DEVELOPMENT (2001)
Skinny Hedgehog, an acyltransferase required for palmitoylation and activity of the Hedgehog signal
Z Chamoun et al.
SCIENCE (2001)
The Hedgehog and Wnt signaling pathways in cancer
J Taipale et al.
NATURE (2001)
Transmembrane molecular pump activity of Niemann-Pick C1 protein
JP Davies et al.
SCIENCE (2000)
Patched represses the Hedgehog signalling pathway by promoting modification of the Smoothened protein
PW Ingham et al.
CURRENT BIOLOGY (2000)
Mapping Sonic hedgehog-receptor interactions by steric interference
RB Pepinsky et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
分享论文
