期刊
NATURE
卷 458, 期 7237, 页码 438-444出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nature07960
关键词
-
资金
- European Molecular Biology Organization (EMBO)
- German Research Foundation (DFG)
- Cluster of Excellence `Macromolecular Complexes' (Goethe University Frankfurt)
The ubiquitin system is a network of proteins dedicated to the ubiquitylation of cellular targets and the subsequent control of numerous cellular functions. The deregulation of components of this elaborate network leads to human pathogenesis, including the development of many types of tumour. Alterations in the ubiquitin system that occur during the initiation and progression of cancer are now being uncovered, and this knowledge is starting to be exploited for both molecular diagnostics and the development of novel strategies to combat cancer.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据