期刊
NATURE
卷 461, 期 7266, 页码 908-915出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nature08537
关键词
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资金
- US National Institutes of Health [NIMH R37 MH60233-06A1, NINDS U24 NS52108]
- US National Institute on Aging
- Dr Miriam & Sheldon G. Adelson Medical Research Foundation
- A. P. Giannini Foundation Medical Research Foundation
- NARSAD
Advances in genetics and genomics have fuelled a revolution in discovery-based, or hypothesis-generating, research that provides a powerful complement to the more directly hypothesis-driven molecular, cellular and systems neuroscience. Genetic and functional genomic studies have already yielded important insights into neuronal diversity and function, as well as disease. One of the most exciting and challenging frontiers in neuroscience involves harnessing the power of large-scale genetic, genomic and phenotypic data sets, and the development of tools for data integration and mining. Methods for network analysis and systems biology offer the promise of integrating these multiple levels of data, connecting molecular pathways to nervous system function.
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