期刊
NATURE
卷 452, 期 7187, 页码 580-589出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nature06917
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资金
- NCI NIH HHS [U24 CA092782, U24 CA092782-07, P01 CA069246-070006, P50 CA086355, P01 CA069246, P50 CA086355-01] Funding Source: Medline
New technologies for imaging molecules, particularly optical technologies, are increasingly being used to understand the complexity, diversity and in vivo behaviour of cancers. 'Omic' approaches are providing comprehensive 'snapshots' of biological indicators, or biomarkers, of cancer, but imaging can take this information a step further, showing the activity of these markers in vivo and how their location changes over time. Advances in experimental and clinical imaging are likely to improve how cancer is understood at a systems level and, ultimately, should enable doctors not only to locate tumours but also to assess the activity of the biological processes within these tumours and to provide 'on the spot' treatment.
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