期刊
NATURAL PRODUCT RESEARCH
卷 29, 期 16, 页码 1567-1570出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2014.983920
关键词
baicalin; wogonin; lipid peroxidation; Scutellaria baicalensis; antioxidant
资金
- Wroclaw Medical University [ST-695]
- KBN [4P05F0061]
- [215259/E-394/SPUB/2014/1]
We evaluated the antioxidant properties of four main flavones from Scutellaria baicalensis: baicalein, wogonin and their glucuronides - baicalin and wogonoside. We used three in vitro assays: free radical scavenging with 2,2-diphenylpicrylhydrazyl radical, transition metal ions reducing power by phosphomolybdenum assay and inhibition of the hydroxyl radical-induced peroxidation of linoleic acid assay. All flavones have antioxidant capacity, which differs depending on the structure and mechanisms of activity. In all tests, only baicalein - the aglycone with three adjacent hydroxyl groups - exhibited consistent antioxidant effect. Wogonin protected linoleic acid against oxidation. Baicalin displayed less potent antioxidant properties whereas wogonoside did not have significant antioxidant activity.
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