期刊
NATURAL PRODUCT RESEARCH
卷 26, 期 10, 页码 913-918出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2010.534096
关键词
Bohadschia vitiensis; bivittoside-D; antifungal activity
资金
- Ministry of Earth Sciences, Government of India, New Delhi
This study was carried out to investigate the antifungal activity of Bohadschia vitiensis Semper whole body extracts, followed by isolation and characterisation of bioactive molecules. The methanol extract of the B. vitiensis showed promising activity in in vitro models against Candida albicans, Cryptococcus neoformans, Sporothrix schenckii, Trichophyton mentagrophytes, Aspergillus fumigatus and Candida parapsilosis. The antifungal activity was found in aqueous fraction against C. albicans, C. neoformans, S. schenckii, T. mentagrophytes and A. fumigatus. The major compound was purified from the aqueous fraction and was identified as bivittoside-D isolated earlier from the animal. It showed promising results against C. neoformans, C. neoformans, S. schenckii, T. mentagrophytes, A. fumigatus and C. parapsilosis.
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