Antibacterial potential of benzoate and phenylethanoid derivatives isolated from Acanthus ilicifolius L. leaf extracts

The antibacterial activities of column chromatography fractions of n-hexane, benzene, chloroform, acetone, ethanol and water extracts from Acanthus ilicifolius were tested against 24 bacterial pathogens. The antibacterial activity was performed using agar diffusion method. Most active fractions were further investigated through UV-Vis, C-13, H-1-NMR, FT-IR for the structural elucidation. The antibacterial activity of the extracts was identified as 6-hydroxy-benzoxazolinone, (Z)-4-coumaric acid 4-O-beta-D-glucopyranoside and 3,5-dimethoxy-4-hydroxy methyl benzoate.