期刊
NATURAL PRODUCT RESEARCH
卷 26, 期 21, 页码 1996-2001出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2011.636747
关键词
valerianaceae; Valeriana jatamansi; iridoid; neuroprotective effect
资金
- Natural Science Foundation of China [30801432]
- Natural Science Foundation of Tianjin, China [09JCZDJC22000]
A new iridoid, jatamandoid A (1), and four known analogues (2-5) were isolated from the roots of Valeriana jatamansi. Their structures were elucidated on the basis of extensive spectroscopic analysis (IR, ESI-MS, HR-ESI-MS, 1-D and 2-D NMR). Five compounds were evaluated and compounds 1, 2 and 5 showed moderate neuroprotective effects against MPP+-induced neuronal SH-SY5Y cell death.
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