期刊
NATURAL PRODUCT RESEARCH
卷 23, 期 12, 页码 1089-1094出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786410802292286
关键词
Erythrina costaricensis; Leguminosae; isoflavonoids; isoflavanones; anti-MRSA activity
Three new isoflavanones, 5,7,3'-trihydroxy-4'-methoxy-6,5'-di(, -dimethylallyl)-isoflavanone (1), 5,3'-dihydroxy-4'-methoxy-5'-,-dimethylallyl-2'',2''-dimethylpyrano[5,6 : 6,7]isoflavanone (2) and 5,3'-dihydroxy-2'',2''-dimethylpyrano[5,6 : 6,7]-2''',2'''-dimethylpyrano[5,6 : 5,4]isoflavanone (3), along with two known isoflavonoids, cristacarpin and euchrenone b10, were isolated from the stems of Erythrina costaricensis. Their structures were established on the basis of spectroscopic evidence. Compound 3 is a rare isoflavanone possessing two 2,2-dimethylpyran moieties. Among the new isoflavanones, compound 1 showed potent antibacterial activity against methicillin-resistant Staphylococcus aureus.
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