期刊
NATURAL PRODUCT REPORTS
卷 28, 期 1, 页码 15-25出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0np00044b
关键词
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资金
- NIH-NIGMS [GM086483]
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM086483] Funding Source: NIH RePORTER
Chlorosulfolipids have been isolated from freshwater algae and from toxic mussels. They appear to have a structural role in algal membranes and have been implicated in Diarrhetic Shellfish Poisoning. Further fascinating aspects of these compounds include their stereochemically complex polychlorinated structures and the resulting strong conformational biases, and their poorly understood (yet surely compelling) biosynthesis. Discussions of each of these topics and of efforts in structural and stereochemical elucidation and synthesis are the subject of this Highlight.
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