4.7 Review

A sea of biosynthesis: marine natural products meet the molecular age

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biotechnology & Applied Microbiology

Isolation and Characterization of the Gene Cluster for Biosynthesis of the Thiopeptide Antibiotic TP-1161

Kerstin Engelhardt et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2010)

Review Biotechnology & Applied Microbiology

Improvement of secondary metabolite production in Streptomyces by manipulating pathway regulation

Yihua Chen et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2010)

Review Biotechnology & Applied Microbiology

Biotechnological doxorubicin production: pathway and regulation engineering of strains for enhanced production

Narayan Prasad Niraula et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2010)

Article Biochemistry & Molecular Biology

High-throughput DNA sequencing - concepts and limitations

Martin Kircher et al.

BIOESSAYS (2010)

Article Biochemistry & Molecular Biology

Identification of the Tirandamycin Biosynthetic Gene Cluster from Streptomyces sp 307-9

Jacob C. Carlson et al.

CHEMBIOCHEM (2010)

Review Microbiology

Engineering of regulatory cascades and networks controlling antibiotic biosynthesis in Streptomyces

Juan-Francisco Martin et al.

CURRENT OPINION IN MICROBIOLOGY (2010)

Article Plant Sciences

Engineering Fluorometabolite Production: Fluorinase Expression in Salinispora tropica Yields Fluorosalinosporamide

Alessandra S. Eustaquio et al.

JOURNAL OF NATURAL PRODUCTS (2010)

Article Chemistry, Multidisciplinary

Shared Biosynthesis of the Saliniketals and Rifamycins in Salinispora arenicola is Controlled by the sare1259-Encoded Cytochrome P450

Micheal C. Wilson et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)

Review Biochemistry & Molecular Biology

Complexity and simplicity in the biosynthesis of enediyne natural products

Zhao-Xun Liang

NATURAL PRODUCT REPORTS (2010)

Review Biochemistry & Molecular Biology

Cyclization of aromatic polyketides from bacteria and fungi

Hui Zhou et al.

NATURAL PRODUCT REPORTS (2010)

Review Biochemistry & Molecular Biology

Marine natural products

John W. Blunt et al.

NATURAL PRODUCT REPORTS (2010)

Review Biochemistry & Molecular Biology

Post-PKS tailoring steps in natural product-producing actinomycetes from the perspective of combinatorial biosynthesis

Carlos Olano et al.

NATURAL PRODUCT REPORTS (2010)

Review Biochemistry & Molecular Biology

Biosynthesis of polyketides by trans-AT polyketide synthases

Joern Piel

NATURAL PRODUCT REPORTS (2010)

Review Biochemistry & Molecular Biology

PKS and NRPS release mechanisms

Liangcheng Du et al.

NATURAL PRODUCT REPORTS (2010)

Review Genetics & Heredity

Computational solutions to large-scale data management and analysis

Eric E. Schadt et al.

NATURE REVIEWS GENETICS (2010)

Article Multidisciplinary Sciences

Genome-minimized Streptomyces host for the heterologous expression of secondary metabolism

Mamoru Komatsua et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Multidisciplinary Sciences

Conformational switch triggered by α-ketoglutarate in a halogenase of curacin A biosynthesis

Dheeraj Khare et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Review Pharmacology & Pharmacy

The odyssey of marine pharmaceuticals: a current pipeline perspective

Alejandro M. S. Mayer et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2010)

Review Chemistry, Multidisciplinary

Structural Perspective on Enzymatic Halogenation

Leah C. Blasiak et al.

ACCOUNTS OF CHEMICAL RESEARCH (2009)

Review Chemistry, Multidisciplinary

The Biosynthetic Logic of Polyketide Diversity

Christian Hertweck

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2009)

Review Biochemistry & Molecular Biology

Recent advances in siderophore biosynthesis

Sarah M. Barry et al.

CURRENT OPINION IN CHEMICAL BIOLOGY (2009)

Review Microbiology

Chasing the treasures of the sea - bacterial marine natural products

Tobias A. M. Gulder et al.

CURRENT OPINION IN MICROBIOLOGY (2009)

Review Biochemistry & Molecular Biology

Exploring the Chemistry and Biology of Vanadium-dependent Haloperoxidases

Jaclyn M. Winter et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Article Chemistry, Medicinal

Function-Oriented Biosynthesis of β-Lactone Proteasome Inhibitors in Salinispora tropica

Markus Nett et al.

JOURNAL OF MEDICINAL CHEMISTRY (2009)

Article Plant Sciences

In Vitro Biosynthesis of Unnatural Enterocin and Wailupemycin Polyketides

John A. Kalaitzis et al.

JOURNAL OF NATURAL PRODUCTS (2009)

Article Chemistry, Multidisciplinary

Pederin-Type Pathways of Uncultivated Bacterial Symbionts: Analysis of O-Methyltransferases and Generation of a Biosynthetic Hybrid

Katrin Zimmermann et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)

Article Chemistry, Multidisciplinary

Biosynthesis of Salinosporamides from α,β-Unsaturated Fatty Acids: Implications for Extending Polyketide Synthase Diversity

Yuan Liu et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)

Review Biochemistry & Molecular Biology

Heterologous expression systems for polyketide synthases

Isao Fujii

NATURAL PRODUCT REPORTS (2009)

Review Biochemistry & Molecular Biology

Mining cyanobacterial genomes for genes encoding complex biosynthetic pathways

John A. Kalaitzis et al.

NATURAL PRODUCT REPORTS (2009)

Review Biochemistry & Molecular Biology

Genomic basis for natural product biosynthetic diversity in the actinomycetes

Markus Nett et al.

NATURAL PRODUCT REPORTS (2009)

Review Biochemistry & Molecular Biology

Ribosomal peptide natural products: bridging the ribosomal and nonribosomal worlds

John A. McIntosh et al.

NATURAL PRODUCT REPORTS (2009)

Review Biochemistry & Molecular Biology

New natural product biosynthetic chemistry discovered by genome mining

Christophe Corre et al.

NATURAL PRODUCT REPORTS (2009)

Review Biochemistry & Molecular Biology

Metabolites from symbiotic bacteria

Joern Piel

NATURAL PRODUCT REPORTS (2009)

Review Biochemistry & Molecular Biology

Structural insights into nonribosomal peptide enzymatic assembly lines

Alexander Koglin et al.

NATURAL PRODUCT REPORTS (2009)

Review Biochemistry & Molecular Biology

Biosynthesis of polyketide synthase extender units

Yolande A. Chan et al.

NATURAL PRODUCT REPORTS (2009)

Article Multidisciplinary Sciences

Metamorphic enzyme assembly in polyketide diversification

Liangcai Gu et al.

NATURE (2009)

Review Multidisciplinary Sciences

Mechanistic considerations of halogenating enzymes

Alison Butler et al.

NATURE (2009)

Article Biochemistry & Molecular Biology

Polyketide assembly lines of uncultivated sponge symbionts from structure-based gene targeting

Katja M. Fisch et al.

NATURE CHEMICAL BIOLOGY (2009)

Review Biotechnology & Applied Microbiology

Drug development from marine natural products

Tadeusz F. Molinski et al.

NATURE REVIEWS DRUG DISCOVERY (2009)

Article Multidisciplinary Sciences

Biosynthesis of the salinosporamide A polyketide synthase substrate chloroethylmalonyl-coenzyme A from S-adenosyl-L-methionine

Alessandra S. Eustaquio et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Chemistry, Multidisciplinary

Mutasynthesis of fluorosalinosporamide, a potent and reversible inhibitor of the proteasome

Alessandra S. Eustaquio et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2008)

Review Biochemistry & Molecular Biology

The fluorinase, the chlorinase and the duf-62 enzymes

Hai Deng et al.

CURRENT OPINION IN CHEMICAL BIOLOGY (2008)

Article Chemistry, Medicinal

Genome mining for novel natural product discovery

Gregory L. Challis

JOURNAL OF MEDICINAL CHEMISTRY (2008)

Article Chemistry, Multidisciplinary

Engineered biosynthesis of antiprotealide and other unnatural salinosporamide proteasome inhibitors

Ryan P. McGlinchey et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)

Article Chemistry, Multidisciplinary

Unraveling the biosynthesis of the sporolide cyclohexenone building block

Ryan P. McGlinchey et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)

Article Chemistry, Multidisciplinary

Biosynthesis and structures of cyclomarins and cyclomarazines, prenylated cyclic peptides of marine actinobacterial origin

Andrew W. Schultz et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)

Review Biochemistry & Molecular Biology

Isoprenoid-like alkylations in polyketide biosynthesis

Christopher T. Calderone

NATURAL PRODUCT REPORTS (2008)

Review Biochemistry & Molecular Biology

Trading molecules and tracking targets in symbiotic interactions

Eric W. Schmidt

NATURE CHEMICAL BIOLOGY (2008)

Article Biochemistry & Molecular Biology

Discovery and characterization of a marine bacterial SAM-dependent chlorinase

Alessandra S. Eustaquio et al.

NATURE CHEMICAL BIOLOGY (2008)

Article Multidisciplinary Sciences

GNAT-like strategy for polyketide chain initiation

Liangcai Gu et al.

SCIENCE (2007)

Article Biochemistry & Molecular Biology

Enzymatic total synthesis of enterocin polyketides

Qian Cheng et al.

NATURE CHEMICAL BIOLOGY (2007)

Article Multidisciplinary Sciences

Genome sequencing reveals complex secondary metabolome in the marine actinomycete Salinispora tropica

Daniel W. Udwary et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Biotechnology & Applied Microbiology

Species-specific secondary metabolite production in marine actinomycetes of the genus Salinispora

Paul R. Jensen et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2007)

Article Multidisciplinary Sciences

The identification of bacillaene, the product of the PksX megacomplex in Bacillus subtilis

Rebecca A. Butcher et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Review Biochemistry & Molecular Biology

Systems biology of antibiotic production by microorganisms

J. Stefan Rokem et al.

NATURAL PRODUCT REPORTS (2007)

Review Biochemistry & Molecular Biology

Type II polyketide synthases: gaining a deeper insight into enzymatic teamwork

Christian Hertweck et al.

NATURAL PRODUCT REPORTS (2007)

Article Biochemistry & Molecular Biology

Natural combinatorial peptide libraries in cyanobacterial symbionts of marine ascidians

Mohamed S. Donia et al.

NATURE CHEMICAL BIOLOGY (2006)

Review Chemistry, Multidisciplinary

Structural biology and chemistry of the terpenoid cyclases

David W. Christianson

CHEMICAL REVIEWS (2006)

Review Chemistry, Multidisciplinary

Nature's inventory of halogenation catalysts: Oxidative strategies predominate

Frederic H. Vaillancourt et al.

CHEMICAL REVIEWS (2006)

Article Plant Sciences

Characterization of the initial enzymatic steps of barbamide biosynthesis

Patricia M. Flatt et al.

JOURNAL OF NATURAL PRODUCTS (2006)

Article Multidisciplinary Sciences

Convergence of isoprene and polyketide biosynthetic machinery:: Isoprenyl-S-carrier proteins in the pksX pathway of Bacillus subtilis

Christopher T. Calderone et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Biotechnology & Applied Microbiology

Structure of trichamide, a cyclic peptide from the bloom-forming cyanobacterium Trichodesmium erythraeum, predicted from the genome sequence

Sebastian Sudek et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2006)

Article Chemistry, Multidisciplinary

Halogenation of unactivated carbon centers in natural product biosynthesis: Trichlorination of leucine during barbamide biosynthesis

DP Galonic et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)

Review Biochemistry & Molecular Biology

Biosynthesis of marine natural products: macroorganisms (Part B)

Bradley S. Moore

NATURAL PRODUCT REPORTS (2006)

Review Biochemistry & Molecular Biology

The biosynthesis, molecular genetics and enzymology of the polyketide-derived metabolites

AM Hill

NATURAL PRODUCT REPORTS (2006)

Review Biochemistry & Molecular Biology

Privileged structures as leads in medicinal chemistry

L Costantino et al.

CURRENT MEDICINAL CHEMISTRY (2006)

Article Multidisciplinary Sciences

Cryptic chlorination by a non-haem iron enzyme during cyclopropyl amino acid biosynthesis

FH Vaillancourt et al.

NATURE (2005)

Article Multidisciplinary Sciences

SyrB2 in syringomycin E biosynthesis is a nonherne FeII α-ketoglutarate- and O2-dependent halogenase

FH Vaillancourt et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Microbiology

Biochemical characterization of a prokaryotic phenylalanine ammonia lyase

LK Xiang et al.

JOURNAL OF BACTERIOLOGY (2005)

Article Multidisciplinary Sciences

Patellamide A and C biosynthesis by a microcin-like pathway in Prochloron didemni, the cyanobacterial symbiont of Lissoclinum patella

EW Schmidt et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Review Chemistry, Multidisciplinary

Molecular mechanisms underlying nonribosomal peptide synthesis: Approaches to new antibiotics

SA Sieber et al.

CHEMICAL REVIEWS (2005)

Review Biochemistry & Molecular Biology

Biosynthesis of marine natural products: microorganisms (Part A)

BS Moore

NATURAL PRODUCT REPORTS (2005)

Article Biochemistry & Molecular Biology

Context-dependent behavior of the enterocin iterative polyketide synthase: A new model for ketoreduction

C Hertweck et al.

CHEMISTRY & BIOLOGY (2004)

Article Multidisciplinary Sciences

Crystal structure and mechanism of a bacterial fluorinating enzyme

CJ Dong et al.

NATURE (2004)

Article Biochemistry & Molecular Biology

The role of vanadium bromoperoxidase in the biosynthesis of halogenated marine natural products

A Butler et al.

NATURAL PRODUCT REPORTS (2004)

Article Chemistry, Multidisciplinary

Natural organohalogens: a new frontier for medicinal agents?

GW Gribble

JOURNAL OF CHEMICAL EDUCATION (2004)

Article Chemistry, Multidisciplinary

Lyngbyatoxin biosynthesis: Sequence of biosynthetic gene cluster and identification of a novel aromatic prenyltransferase

DJ Edwards et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)

Review Plant Sciences

Marine natural products and related compounds in clinical and advanced preclinical trials

DJ Newman et al.

JOURNAL OF NATURAL PRODUCTS (2004)

Article Chemistry, Multidisciplinary

Vanadium bromoperoxidase-catalyzed biosynthesis of halogenated marine natural products

JN Carter-Franklin et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)

Article Multidisciplinary Sciences

Antitumor polyketide biosynthesis by an uncultivated bacterial symbiont of the marine sponge Theonella swinhoei

J Piel et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Multidisciplinary Sciences

EncM, a versatile enterocin biosynthetic enzyme involved in Favorskii oxidative rearrangement, aldol condensation, and heterocycle-forming reactions

L Xiang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Biotechnology & Applied Microbiology

Characterization of the nodularin synthetase gene cluster and proposed theory of the evolution of cyanobacterial hepatotoxins

MC Moffitt et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2004)

Review Biochemistry & Molecular Biology

Metabolites from symbiotic bacteria

J Piel

NATURAL PRODUCT REPORTS (2004)

Review Microbiology

Biosynthesis of nonribosomal peptides

R Finking et al.

ANNUAL REVIEW OF MICROBIOLOGY (2004)

Article Chemistry, Multidisciplinary

Mutasynthesis of enterocin and wailupemycin analogues

JA Kalaitzis et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2003)

Review Chemistry, Organic

Nonribosomal peptides from marine sponges

S Matsunaga et al.

CURRENT ORGANIC CHEMISTRY (2003)

Article Biotechnology & Applied Microbiology

Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis

H Ikeda et al.

NATURE BIOTECHNOLOGY (2003)

Review Biochemistry & Molecular Biology

Diversity of the biosynthesis of the isoprene units

T Kuzuyama et al.

NATURAL PRODUCT REPORTS (2003)

Article Multidisciplinary Sciences

A polyketide synthase-peptide synthetase gene cluster from an uncultured bacterial symbiont of Paederus beetles

J Piel

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Article Biochemistry & Molecular Biology

Inactivation, complementation, and heterologous expression of encP, a novel bacterial phenylalanine ammonia-lyase gene

LK Xiang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Biotechnology & Applied Microbiology

Molecular evidence for a uniform microbial community in sponges from different oceans

U Hentschel et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2002)

Article Multidisciplinary Sciences

Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)

SD Bentley et al.

NATURE (2002)

Article Plant Sciences

Localization studies of bioactive cyclic peptides in the ascidian Lissoclinum patella

CE Salomon et al.

JOURNAL OF NATURAL PRODUCTS (2002)

Article Chemistry, Organic

Mutational analysis of the enterocin Favorskii biosynthetic rearrangement

LK Xiang et al.

ORGANIC LETTERS (2002)

Article Biochemistry & Molecular Biology

The Pfam Protein Families Database

A Bateman et al.

NUCLEIC ACIDS RESEARCH (2002)

Article Biochemistry & Molecular Biology

TIGRFAMs: a protein family resource for the functional identification of proteins

DH Haft et al.

NUCLEIC ACIDS RESEARCH (2001)

Review Biochemistry & Molecular Biology

Polyketide biosynthesis: a millennium review

J Staunton et al.

NATURAL PRODUCT REPORTS (2001)

Article Biochemistry & Molecular Biology

Biosynthesis of fatty acids in the docosahexaenoic acid-producing bacterium Moritella marina strain MP-I

N Morita et al.

BIOCHEMICAL SOCIETY TRANSACTIONS (2000)

Article Chemistry, Multidisciplinary

Natural metabolic diversity encoded by the enterocin biosynthesis gene cluster

J Piel et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2000)

Review Biochemistry & Molecular Biology

Highlights of marine natural products chemistry (1972-1999)

DJ Faulkner

NATURAL PRODUCT REPORTS (2000)