相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Imperfect pseudo-merohedral twinning in crystals of fungal fatty acid synthase
Simon Jenni et al.
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2009)
Type II Thioesterase ScoT, Associated with Streptomyces coelicolor A3(2) Modular Polyketide Synthase Cpk, Hydrolyzes Acyl Residues and Has a Preference for Propionate
Magdalena Kotowska et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2009)
In Vitro Kinetic Analysis of Substrate Specificity in Enterobactin Biosynthetic Lower Pathway Enzymes Provides Insight into the Biochemical Function of the Hot Dog-Fold Thioesterase EntH
Danqi Chen et al.
BIOCHEMISTRY (2009)
Preferential Hydrolysis of Aberrant Intermediates by the Type II Thioesterase in Escherichia coli Nonribosomal Enterobactin Synthesis: Substrate Specificities and Mutagenic Studies on the Active-Site Residues
Zu-Feng Guo et al.
BIOCHEMISTRY (2009)
Mapping the Limits of Substrate Specificity of the Adenylation Domain of TycA
Benoit R. M. Villiers et al.
CHEMBIOCHEM (2009)
The Structural Diversity of Acidic Lipopeptide Antibiotics
Matthias Strieker et al.
CHEMBIOCHEM (2009)
Revisiting the modularity of modular polyketide synthases
Chaitan Khosla et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2009)
TioS T-TE - a prototypical thioesterase responsible for cyclodimerization of the quinoline- and quinoxaline-type class of chromodepsipeptides
Lars Robbel et al.
FEBS JOURNAL (2009)
Cascade Reactions during Coronafacic Acid Biosynthesis: Elongation, Cyclization, and Functionalization during Cfa7-Catalyzed Condensation
Eric R. Strieter et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)
A PLP-Dependent Polyketide Chain Releasing Mechanism in the Biosynthesis of Mycotoxin Fumonisins in Fusarium verticillioides
Ryan Gerber et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)
Conformational flexibility of metazoan fatty acid synthase enables catalysis
Edward J. Brignole et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2009)
Decoding and engineering tetracycline biosynthesis
Lauren B. Pickens et al.
METABOLIC ENGINEERING (2009)
Structural modification of acyl carrier protein by butyryl group
Bai-Nan Wu et al.
PROTEIN SCIENCE (2009)
The chemical versatility of natural-product assembly lines
Christopher T. Walsh
ACCOUNTS OF CHEMICAL RESEARCH (2008)
Selective Removal of Aberrant Extender Units by a Type II Thioesterase for Efficient FR-008/Candicidin Biosynthesis in Streptomyces sp Strain FR-008
Yongjun Zhou et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2008)
β-Hydroxylation of the Aspartyl Residue in the Phytotoxin Syringomycin E: Characterization of Two Candidate Hydroxylases AspH and SyrP in Pseudomonas syringae
Gitanjali M. Singh et al.
BIOCHEMISTRY (2008)
Inhibition kinetics and emodin cocrystal structure of a type II polyketide ketoreductase
Tyler Paz Korman et al.
BIOCHEMISTRY (2008)
Crystal Structure and Enantiomer Selection by D-Alanyl Carrier Protein Ligase DltA from Bacillus cereus
Liqin Du et al.
BIOCHEMISTRY (2008)
An ACP Structural Switch: Conformational Differences between the Apo and Holo Forms of the Actinorhodin Polyketide Synthase Acyl Carrier Protein
Simon E. Evans et al.
CHEMBIOCHEM (2008)
Protein-protein interactions in multienzyme megasynthetases
Kira J. Weissman et al.
CHEMBIOCHEM (2008)
The multienzyme architecture of eukaryotic fatty acid synthases
Marc Leibundgut et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2008)
Regiospecific O-methylation of naphthoic acids catalyzed by NcsB1, an O-methyltransferase involved in the biosynthesis of the enediyne antitumor antibiotic neocarzinostatin
Yinggang Luo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Crystal Structure of DltA IMPLICATIONS FOR THE REACTION MECHANISM OF NON-RIBOSOMAL PEPTIDE SYNTHETASE ADENYLATION DOMAINS
Huma Yonus et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Crystal Structure of the Erythromycin Polyketide Synthase Dehydratase
Adrian Keatinge-Clay
JOURNAL OF MOLECULAR BIOLOGY (2008)
Harnessing the chemical activation inherent to carrier protein-bound thioesters for the characterization of lipopeptide fatty acid tailoring enzymes
Florian Kopp et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
Stereospecificity of ketoreductase domains 1 and 2 of the tylactone modular polyketide synthase
Roselyne Castonguay et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
cis-Δ2,3-double bond of phoslactomycins is generated by a post-PKS tailoring enzyme
Nadaraj Palaniappan et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
Thioesterase-like role for fungal PKS-NRPS hybrid reductive domains
James W. Sims et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
Myxochelin biosynthesis:: Direct evidence for two- and four-electron reduction of a carrier protein-bound thioester
Yanyan Li et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
An eight residue fragment of an acyl carrier protein suffices for post-translational introduction of fluorescent pantetheinyl arms in protein modification in vitro and in vivo
Zhe Zhou et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
Biochemistry - Fit for an enzyme
Shiven Kapur et al.
NATURE (2008)
Dynamic thiolation-thioesterase structure of a non-ribosomal peptide synthetase
Dominique P. Frueh et al.
NATURE (2008)
Structural basis for the selectivity of the external thioesterase of the surfactin synthetase
Alexander Koglin et al.
NATURE (2008)
Crystal structure and functional analysis of tetracenomycin ARO/CYC: Implications for cyclization specificity of aromatic polyketides
Brian Douglas Ames et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
The crystal structure of a mammalian fatty acid synthase
Timm Maier et al.
SCIENCE (2008)
Crystal structure of the termination module of a nonribosomal peptide synthetase
Alan Tanovic et al.
SCIENCE (2008)
Multienzyme docking in hybrid megasynthetases
Carsten D. Richter et al.
NATURE CHEMICAL BIOLOGY (2008)
The hotdog thioesterase EntH (YbdB) plays a role in vivo in optimal enterobactin biosynthesis by interacting with the ArCP domain of EntB
Damien Leduc et al.
JOURNAL OF BACTERIOLOGY (2007)
Solution structure and proposed domain-domain recognition interface of an acyl carrier protein domain from a modular polyketide synthase
Viktor Y. Alekseyev et al.
PROTEIN SCIENCE (2007)
A transglutaminase homologue as a condensation catalyst in antibiotic assembly lines
Pascal D. Fortin et al.
NATURE (2007)
Structural and mechanistic analysis of protein interactions in module 3 of the 6-deoxyerythronolide B synthase
Yinyan Tang et al.
CHEMISTRY & BIOLOGY (2007)
A tylosin ketoreductase reveals how chirality is determined in polyketides
Adrian T. Keatinge-Clay
CHEMISTRY & BIOLOGY (2007)
Directed evolution of aryl carrier proteins in the enterobactin synthetase
Zhe Zhou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Structural and functional insights into a peptide bond-forming bidomain from a nonribosomal peptide synthetase
Stefan A. Samel et al.
STRUCTURE (2007)
Structure-based dissociation of a type I polyketide synthase module
Alice Y. Chen et al.
CHEMISTRY & BIOLOGY (2007)
Autonomous folding of interdomain regions of a modular polyketide synthase
Carsten D. Richter et al.
FEBS JOURNAL (2007)
Structure of fungal fatty acid synthase and implications for iterative substrate shuttling
Simon Jenni et al.
SCIENCE (2007)
Structural basis for substrate delivery by acyl carrier protein in the yeast fatty acid synthase
Marc Leibundgut et al.
SCIENCE (2007)
Mechanistic and structural basis of stereospecific Cβ-hydroxylation in calcium-dependent antibiotic, a daptomycin-type lipopeptide
Matthias Strieker et al.
ACS CHEMICAL BIOLOGY (2007)
An asparagine oxygenase (AsnO) and a 3-hydroxyasparaginyl phosphotransferase (HasP) are involved in the biosynthesis of calcium-dependent lipopeptide antibiotics
Joanne M. Neary et al.
MICROBIOLOGY-SGM (2007)
Chlorination by a long-lived intermediate in the mechanism of flavin-dependent halogenases
Ellen Yeh et al.
BIOCHEMISTRY (2007)
Two interconverting Fe(IV) intermediates in aliphatic chlorination by the halogenase CytC3
Danica P. Galonic et al.
NATURE CHEMICAL BIOLOGY (2007)
Structural studies of fatty acyl-(acyl carrier protein) thioesters reveal a hydrophobic binding cavity that can expand to fit longer substrates
Anna Roujeinikova et al.
JOURNAL OF MOLECULAR BIOLOGY (2007)
Macrocyclization strategies in polyketide and nonribosomal peptide biosynthesis
Florian Kopp et al.
NATURAL PRODUCT REPORTS (2007)
The iterative gramicidin S thioesterase catalyzes peptide ligation and cyclization
Katharina M. Hoyer et al.
CHEMISTRY & BIOLOGY (2007)
New antibiotics from bacterial natural products
Jon Clardy et al.
NATURE BIOTECHNOLOGY (2006)
Structural and functional studies on SCO1815:: A β-ketoacyl-acyl carrier protein reductase from Streptomyces coelicolor A3(2)
Yinyan Tang et al.
BIOCHEMISTRY (2006)
Impact of epimerization domains on the intermodular transfer of enzyme-bound intermediates in nonribosomal peptide synthesis
Daniel B. Stein et al.
CHEMBIOCHEM (2006)
Localized protein interaction surfaces on the EntB carrier protein revealed by combinatorial mutagenesis and selection
Jonathan R. Lai et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)
Structural characterization of enterobactin hydrolase IroE
N. A. Larsen et al.
BIOCHEMISTRY (2006)
A biosynthetic gene cluster for the acetyl-CoA carboxylase inhibitor andrimid
Mi Jin et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)
Assembly-line enzymology for polyketide and nonribosomal peptide antibiotics: Logic, machinery, and mechanisms
Michael A. Fischbach et al.
CHEMICAL REVIEWS (2006)
Nature's inventory of halogenation catalysts: Oxidative strategies predominate
Frederic H. Vaillancourt et al.
CHEMICAL REVIEWS (2006)
Interdomain communication between the thiolation and thioesterase domains of EntF explored by combinatorial mutagenesis and selection
Zhe Zhou et al.
CHEMISTRY & BIOLOGY (2006)
Myxovirescin A biosynthesis is directed by hybrid polyketide synthases/nonribosomal peptide synthetase, 3-hydroxy-3-methylglutaryl-CoA synthases, and trans-acting acyltransferases
Vesna Simunovic et al.
CHEMBIOCHEM (2006)
The 2.7-Å crystal structure of a 194-kDa homodimeric fragment of the 6-deoxyerythronolide B synthase
Yinyan Tang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Determination of the crystal structure of EntA, a 2,3-dihydro-2,3-dihydroxybenzoic acid dehydrogenase from Escherichia coli
Jesse A. Sundlov et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2006)
The thioesterase domain of the fengycin biosynthesis cluster: A structural base for the macrocyclization of a non-ribosomal lipopeptide
Stefan A. Samel et al.
JOURNAL OF MOLECULAR BIOLOGY (2006)
Formylation domain: An essential modifying enzyme for the nonribosomal biosynthesis of linear gramicidin
Georg Schoenafinger et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)
Solution structures of conformationally equilibrium forms of holo-acyl carrier protein (PfACP) from Plasmodium falciparum provides insight into the mechanism of activation of ACPs
Alok Kumar Sharma et al.
BIOCHEMISTRY (2006)
Non-uniformly sampled double-TROSY hNcaNH experiments for NMR sequential assignments of large proteins
DP Frueh et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)
Dichlorination and bromination of a threonyl-S-carrier protein by the non-heme FeII halogenase SyrB2
Frederic H. Vaillancourt et al.
CHEMBIOCHEM (2006)
Solution structure of As11650, an acyl carrier protein from Anabaena sp PCC 7120 with a variant phosphopantetheinylation-site sequence
MA Johnson et al.
PROTEIN SCIENCE (2006)
Solution structures of spinach acyl carrier protein with decanoate and stearate
GA Zornetzer et al.
BIOCHEMISTRY (2006)
Conformational switches modulate protein interactions in peptide antibiotic synthetases
A Koglin et al.
SCIENCE (2006)
A protein interaction surface in nonribosomal peptide synthesis mapped by combinatorial mutagenesis and selection
JR Lai et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
The structure of a ketoreductase determines the organization of the β-carbon processing enzymes of modular polyketide synthases
AT Keatinge-Clay et al.
STRUCTURE (2006)
Structure of the EntB multidomain nonribosomal peptide synthetase and functional analysis of its interaction with the EntE adenylation domain
EJ Drake et al.
CHEMISTRY & BIOLOGY (2006)
Crystal structure of the non-haem iron halogenase SyrB2 in syringomycin biosynthesis
LC Blasiak et al.
NATURE (2006)
Extender unit and acyl carrier protein specificity of ketosynthase domains of the 6-deoxyerythronolide B synthase
AY Chen et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)
Architecture of a fungal fatty acid synthase at 5 Å resolution
S Jenni et al.
SCIENCE (2006)
Architecture of mammalian fatty acid synthase at 4.5 Å resolution
T Maier et al.
SCIENCE (2006)
Chemoenzymatic and template-directed synthesis of bioactive macrocyclic peptides
J Grünewald et al.
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2006)
Macrolactonization to 10-deoxymethynolide catalyzed by the recombinant thioesterase of the picromycin/methymycin polyketide synthase
WG He et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2006)
Determination of all nOes in H-1-C-13-Me-ILV-U-H-2-N-15 proteins with two time-shared experiments
DP Frueh et al.
JOURNAL OF BIOMOLECULAR NMR (2006)
Polyketide double bond biosynthesis. Mechanistic analysis of the dehydratase-containing module 2 of the picromycin/methymycin polyketide synthase
JQ Wu et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)
Generation of D amino acid residues in assembly of arthrofactin by dual condensation/epimerization domains
CJ Balibar et al.
CHEMISTRY & BIOLOGY (2005)
Excision of the epothilone synthetase B cyclization domain and demonstration of in trans condensation/cyclodehydration activity
WL Kelly et al.
BIOCHEMISTRY (2005)
Elucidating the substrate specificity and condensation domain activity of FkbP, the FK520 pipecolate-incorporating enzyme
GJ Gatto et al.
BIOCHEMISTRY (2005)
In vitro characterization of IroB, a pathogen-associated C-glycosyltransferase
MA Fischbach et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Structure-based mutational analysis of the 4′-phosphopantetheinyl transferases Sfp from Bacillus subtilis:: Carrier protein recognition and reaction mechanism
MR Mofid et al.
BIOCHEMISTRY (2004)
Mutational analysis of a type II thioesterase associated with nonribosomal peptide synthesis
U Linne et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2004)
Polyketide and nonribosomal peptide antibiotics: Modularity and versatility
CT Walsh
SCIENCE (2004)
The linear pentadecapeptide gramicidin is assembled by four multimodular nonribosomal peptide synthetases that comprise 16 modules with 56 catalytic domains
N Kessler et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
The crystal structure of the actIII actinorhodin polyketide reductase:: Proposed mechanism for ACP and polyketide binding
AT Hadfield et al.
STRUCTURE (2004)
Initiation of surfactin biosynthesis and the role of the SrfD-thioesterase protein
S Steller et al.
BIOCHEMISTRY (2004)
Type II thioesterase restores activity of a NRPS module stalled with an aminoacyl-S-enzyme that cannot be elongated
E Yeh et al.
CHEMBIOCHEM (2004)
An antibiotic factory caught in action
A Keatinge-Clay et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2004)
Portability of oxidase domains in nonribosomal peptide synthetase modules
TL Schneider et al.
BIOCHEMISTRY (2004)
Mutational analysis of peptidyl carrier protein and acyl carrier protein synthase unveils residues involved in protein-protein recognition
R Finking et al.
BIOCHEMISTRY (2004)
Macrolactamization of glycosylated peptide thioesters by the thioesterase domain of tyrocidine synthetase
H Lin et al.
CHEMISTRY & BIOLOGY (2004)
Structural analysis of actinorhodin polyketide ketoreductase: Cofactor binding and substrate specificity
TP Korman et al.
BIOCHEMISTRY (2004)
Selective interaction between nonribosomal peptide syntheltases is facilitated by short commuinication-mediating domains
M Hahn et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Hybrid nonribosomal peptide-polyketide interfaces in epothilone biosynthesis: Minimal requirements at N and C termini of EpoB for elongation
F Liu et al.
CHEMISTRY & BIOLOGY (2004)
Biosynthesis of nonribosomal peptides
R Finking et al.
ANNUAL REVIEW OF MICROBIOLOGY (2004)
Chirality of peptide bond-forming condensation domains in nonribosomal peptide synthetases:: The C5 domain of tyrocidine synthetase is a DCL catalyst
SL Clugston et al.
BIOCHEMISTRY (2003)
Epimerization of an L-cysteinyl to a D-cysteinyl residue during thiazoline ring formation in siderophore chain elongation by pyochelin synthetase from Pseudomonas aeruginosa
HM Patel et al.
BIOCHEMISTRY (2003)
Oxidase domains in epothilone and bleomycin biosynthesis: Thiazoline to thiazole oxidation during chain elongation
TL Schneider et al.
BIOCHEMISTRY (2003)
Solution structure and dynamics of oxytetracycline polyketide synthase acyl carrier protein from Streptomyces rimosus
SC Findlow et al.
BIOCHEMISTRY (2003)
Mechanistic analysis of acyl transferase domain exchange in polyketide synthase modules
M Hans et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2003)
Intermodular communication in modular polyketide synthases: Structural and mutational analysis of linker mediated protein-protein recognition
P Kumar et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2003)
Epothilone C macrolactonization and hydrolysis are catalyzed by the isolated thioesterase domain of epothilone polyketide synthase
CN Boddy et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2003)
Dissection of the EntF condensation domain boundary and active site residues in nonribosomal peptide synthesis
ED Roche et al.
BIOCHEMISTRY (2003)
Vancomycin assembly: Nature's way
BK Hubbard et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2003)
Biochemical evidence for an editing role of thioesterase II in the biosynthesis of the polyketide pikromycin
BS Kim et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Regeneration of misprimed nonribosomal peptide synthetases by type II thioesterases
D Schwarzer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Crystal structure of DhbE, an archetype for aryl acid activating domains of modular nonribosomal peptide synthetases
JJ May et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
The structure of VibH represents nonribosomal peptide synthetase condensation, cyclization and epimerization domains
TA Keating et al.
NATURE STRUCTURAL BIOLOGY (2002)
Type II thioesterase from Streptomyces coelicolor A3(2)
M Kotowska et al.
MICROBIOLOGY-SGM (2002)
Recognition of hybrid peptidyl carrier proteins/Acyl carrier proteins in nonribosomal peptide synthetase modules by the 4′-phophopantetheinyl transferases AcpS and Sfp
MR Mofid et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
The thioesterase domain from a nonribosomal peptide synthetase as a cyclization catalyst for integrin binding peptides
RM Kohli et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Crystal structure of the macrocycle-forming thioesterase domain of the erythromycin polyketide synthase: Versatility from a unique substrate channel
SC Tsai et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
VibD and VibH are required for late steps in vibriobactin biosynthesis in Vibrio cholerae
EE Wyckoff et al.
JOURNAL OF BACTERIOLOGY (2001)
Peptide cyclization catalysed by the thioesterase domain of tyrocidine synthetase
JW Trauger et al.
NATURE (2000)
The EntF and EntE adenylation domains of Escherichia coli enterobactin synthetase:: Sequestration and selectivity in acyl-AMP transfers to thiolation domain cosubstrates
DE Ehmann et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
分享论文
