期刊
NANOTOXICOLOGY
卷 6, 期 2, 页码 134-143出版社
TAYLOR & FRANCIS LTD
DOI: 10.3109/17435390.2011.562327
关键词
Oxidative stress; enzymatic and non-enzymatic antioxidants; copper nanoparticles; copper; Enchytraeids
资金
- Danish Strategic Research Council through the NABIIT [2006-06-0015]
- NANOkA [PTDC/BIA-BEC/103716/2008]
In the present study, the main goal was to compare the effects of ionic copper versus copper nanoparticles in Enchytraeus albidus assessing the effect at the biomarker level, testing different concentrations and exposure times. Measured parameters were lipid peroxidation (LPO), total, reduced and oxidized glutathione content (TG, GSH and GSSG), the enzymatic activity of superoxide dismutase (SOD), catalase (CAT), glutathione reductase (GR), glutathione peroxidase (GPx), glutathione S-transferases (GSTs) and cholinesterases (ChEs). Results showed that both salt-and nano-copper caused oxidative stress and damage to E. albidus, as confirmed by LPO levels, and effects could be discriminated between the copper forms. Nevertheless and despite the visible discrimination between nano and the salt form (time and exposure dependent), there was no single or a set of biomarkers that provided the best discrimination.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据