期刊
NANOTECHNOLOGY
卷 24, 期 41, 页码 -出版社
IOP PUBLISHING LTD
DOI: 10.1088/0957-4484/24/41/415101
关键词
-
资金
- NIH-National Human Genome Research Institute
- National Science Foundation
- US Department of Energy
We suggest the discrimination of single DNA bases via transverse ionic transport, namely by detecting the ionic current that flows in a channel while a single-stranded DNA is driven through an intersecting nanochannel. Our all-atom molecular dynamics simulations indeed show that the ionic currents of the four bases are statistically distinct, thus offering another possible approach to sequencing DNA.
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