期刊
NANOTECHNOLOGY
卷 23, 期 45, 页码 -出版社
IOP PUBLISHING LTD
DOI: 10.1088/0957-4484/23/45/455301
关键词
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资金
- National Science Foundation [CBET-0966723, CMMI-0969958]
- Directorate For Engineering [0969958] Funding Source: National Science Foundation
- Div Of Civil, Mechanical, & Manufact Inn [0969958] Funding Source: National Science Foundation
We present a novel approach to the fabrication of zero-mode waveguides (ZMWs) using inexpensive processing techniques. Our method is capable of rapid fabrication of circular nanoapertures with diameters ranging from 70 nm to 2 mu m, allowing us to perform a detailed characterization of the dependence of the fluorescence emission on the waveguide diameter. We also validated the use of the fabricated ZMWs by detecting single molecule binding events with a signal-to-noise ratio of ten.
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