期刊
NANOTECHNOLOGY
卷 20, 期 29, 页码 -出版社
IOP PUBLISHING LTD
DOI: 10.1088/0957-4484/20/29/295101
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资金
- Air Force Office of Scientific Research
To add to the understanding of the properties of functionalized carbon nanotubes in biological applications, we report a monotonic pH sensitivity of the intracellular fluorescence emission of single-walled carbon nanotube-fluorescein carbazide (SWCNT-FC) conjugates in human ovarian cancer cells. Light-stimulated intracellular hydrolysis of the amide linkage and localized intracellular pH changes are proposed as mechanisms. SWCNT-FC conjugates may serve as intracellular pH sensors.
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