期刊
NANOSCALE
卷 10, 期 10, 页码 4607-4641出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c7nr07348h
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资金
- Alexander Graham Bell Canada Graduate Scholarships-Doctoral (CGS D) from the Natural Sciences and Engineering Research Council of Canada (NSERC)
- Groupe de recherche universitaire sur le medicament (GRUM)
- UdeM
- Canada Graduate Scholarships-Master's (CGS M) from NSERC
- Fonds de recherche du Quebec - Nature et technologies (FRQNT)
DNA switches are ideally suited for numerous nanotechnological applications, and increasing efforts are being directed toward their engineering. In this review, we discuss how to engineer these switches starting from the selection of a specific DNA-based recognition element, to its adaptation and optimisation into a switch, with applications ranging from sensing to drug delivery, smart materials, molecular transporters, logic gates and others. We provide many examples showcasing their high programmability and recent advances towards their real life applications. We conclude with a short perspective on this exciting emerging field.
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