期刊
NANOSCALE
卷 3, 期 10, 页码 4069-4073出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1nr10718f
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资金
- Discovery Project
- Australian Research Council [DP0879769]
We demonstrate an efficient synthesis of novel layered double hydroxide mesoporous silica core-shell nanostructures (LDH@mSiO(2)) that have a hexagonal MgAl-LDH nanoplate core and an ordered mesoporous silica shell with perpendicularly oriented channels via a surfactant-templating method. Transmission electron microscopy, X-ray diffraction and N-2 sorption analyses confirmed that the obtained nanostructures have uniform accessible mesopores (similar to 2.2 nm), high surface area (similar to 430 m(2) g(-1)), and large pore volume (similar to 0.22 cm(3) g(-1)). Investigations of drug release and bio-imaging showed that this material has a slow release effect of ibuprofen and good biocompatibility. This work provides an economical approach to fabricate LDH@mSiO(2) core-shell nanostructures, which may have great potential in broad drug delivery and hyperthermia therapy applications.
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