期刊
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE
卷 5, 期 4, 页码 452-456出版社
ELSEVIER
DOI: 10.1016/j.nano.2009.01.012
关键词
Bionanoparticles; Staphylococcus aureus; Ultraviolet-visible spectrophotometry; Atomic force microscopy; Antimicrobial activity
Silver bionanoparticles (AgNPs) have been known to have inhibitory and bactericidal effects. Resistance to antimicrobial agents by pathogenic bacteria has emerged in recent years and is a major health problem. This report focuses on the synthesis of metallic bionanoparticles of silver using a reduction of aqueous Ag+ ion with the culture supernatants of Staphylococcus aureus. The bioreduction of the Ag+ ions in the solution was monitored in the aqueous component and the spectrum of the solution measured through ultraviolet-visible spectrophotometry and characterized by atomic force microscopy. The AgNPs were evaluated for their antimicrobial activities against different pathogenic organisms. The most sensitive antimicrobial activity has been observed against methicillin-resistant S. aureus followed by methicillin-resistant Staphylococcus epidermidis and Streptococcus pyogenes, whereas only moderate antimicrobial activity was seen against Salmonella typhi and Klebsiella pneumoniae. From the Clinical Editor: Silver bionanoparticles (AgNPs) were evaluated for their antimicrobial activities against different pathogenic organisms. The most sensitive antimicrobial activity has been observed against methicillin-resistant S. aureus followed by methicillin-resistant Staphylococcus epidermidis and Streptococcus pyogenes, whereas only moderate antimicrobial activity was seen against Salmonella typhi and Klebsiella pneumoniae. (C) 2009 Published by Elsevier Inc.
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