期刊
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE
卷 4, 期 3, 页码 237-240出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.nano.2008.04.005
关键词
Antibacterial; Caries; Silver nanoparticles; Streptococcus
资金
- Universidad Autonoma de San Luis Potos
Dental caries is a worldwide public health problem for which Streptococcus mutans has been identified as the possible infectious etiology. In recent years nanotechnology has permitted the development of new properties of materials. The objective of this study was to compare the bactericidal and bacteriostatic effects of nanoparticles of silver, zinc oxide, and gold on S. mutans. We used the liquid dilution method to find the minimum inhibitory concentrations (MICs) and with subcultures obtained the minimum bactericidal concentrations (MBCs). For silver the results showed an average MIC of 4.86 +/- 2.71 mu g/mL and MBC of 6.25 mu g/mL; for zinc the MIC was 500 +/- 306.18 mu g/mL and MBC of 500 mu g/mL; the gold nanoparticles demonstrated an effect only at an initial concentration of 197 mu g/mL. We established a higher antimicrobial effect against S. mutans of silver nanoparticles at lower concentrations than gold or zinc, which would allow achieving important clinical effects with a reduced toxicity. (C) 2008 Elsevier Inc. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据