Recent advances in syntheses and therapeutic applications of multifunctional porous hollow nanoparticles

This paper reviews recent advances in the synthesis of porous hollow nanoparticles (PHNPs) of iron oxide and Au for biomedical applications. It first summarizes the synthesis and characterization of various PHNPs of iron oxide and Au. It then outlines the common chemistry applied to make these PHNPs biocompatible and target-specific. Finally the review presents several representative examples to highlight the applications of these PHNPs for drug delivery and for hyperthermia cancer therapy. Published by Elsevier Ltd.