期刊
NANO RESEARCH
卷 11, 期 10, 页码 5240-5257出版社
TSINGHUA UNIV PRESS
DOI: 10.1007/s12274-018-2179-5
关键词
natural particulates; nanotechnology; bioinspired; drug delivery; biomedical application
类别
资金
- National Natural Science Foundation of China [81673381]
- Natural Science Foundation of Jiangsu Province of China for Distinguished Young Scholars [BK20150029]
- Program for Jiangsu Province Innovative Research Talents
- Program for Jiangsu Province Innovative Research Team
Spurred by numerous achievements in nanoscience and nanotechnology, the evolution of nanoparticulate drug delivery systems (nano-DDSs) is in its rapid growth period and attracting considerable attention due to their unique advantages in biomedical applications. Natural particulates ranging from mammalian cells to bacteria possess their own distinctive delivery processes and mechanisms, which inspires more design and development of cell-based DDSs by integrating the innate functions of cells with the nanoscale characteristics of nanoparticles. In this review article, we focus on the recent advances in cell-based DDSs for site-specific delivery of therapeutics and enhanced treatment of diseases. The promise and perils of cell-based DDSs are also discussed.
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