期刊
NANO LETTERS
卷 14, 期 8, 页码 4918-4922出版社
AMER CHEMICAL SOC
DOI: 10.1021/nl502720s
关键词
Sensor; nanoparticle; luminescence; TNT; picric acid; RDX
类别
资金
- Office of Naval Research, USA
- NanoSensoMach ERC Advanced Grant under the EC [267574]
Luminescent Ag nanoclusters (NCs) stabilized by nucleic acids are implemented as optical labels for the detection of the explosives picric acid, trinitrotoluene (TNT), and hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX). The sensing modules consist of two parts, a nucleic acid with the nucleic acid-stabilized Ag NCs and a nucleic acid functionalized with electron-donating units, including L-DOPA, L-tyrosine and 6-hydroxy-L-DOPA, self-assembled on a nucleic acid scaffold. The formation of donor-acceptor complexes between the nitro-substituted explosives, exhibiting electron. acceptor properties, and the electron-donating sites, associated with the sensing modules, concentrates the explosives in close proximity to the Ag NCs. This leads to the electron-transfer quenching of the luminescence of the Ag NCs by the explosive molecule. The quenching of the luminescence of the Ag NCs provides a readout signal for the sensing process. The sensitivities of the analytical platforms are controlled by the electron-donating properties of the donor substituents, and 6-hydroxy-L-DOPA was found to be the most sensitive donor. Picric acid, TNT, and RDX are analyzed with detection limits corresponding to 5.2 X 10(-12) M, 1.0 x 10(-12) M, and 3.0 x 10(-12) M, respectively, using the 6-hydroxy-L-DOPA-modified Ag NCs sensing module.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据