期刊
NANO LETTERS
卷 12, 期 4, 页码 1845-1850出版社
AMER CHEMICAL SOC
DOI: 10.1021/nl204203t
关键词
Silicon nanowires; hyperthermia agent; cancer photothermal therapy; near-infrared; nanobioapplications
类别
资金
- National Basic Research Program of China (973 Program) [2012CB932400, 2012CB932600]
- NSFC [30900338, 51132006, 51072126]
- Research Grants Council of HKSAR [CityU5/CRF/08, N_CityU108/08, CityU 101608]
- Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD)
Near-infrared (NIR) hyperthermia agents are of current interest because they hold great promise as highly efficacious tools for cancer photothermal therapy. Although various agents have been reported, a practical NIR hyperthermia agent is yet unavailable. Here, we present the first demonstration that silicon nanomaterials-based NIR hyperthermia agent, that is, gold nanoparticles-decorated silicon nanowires (AuNPs@SiNWs), is capable of high-efficiency destruction of cancer cells. AuNPs@SiNWs are found to possess strong optical absorbance in the NIR spectral window, producing sufficient heat under NIB. irradiation. AuNPs@SiNWs are explored as novel NIR hyperthermia agents for photothermal ablation of tumor cells. In particular, three different cancer cells treated with AuNPs@SiNWs were completely destructed within 3 min of NIR irradiation, demonstrating the exciting potential of AuNPs@SiNWs for NIR hyperthermia agents.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据