期刊
NANO LETTERS
卷 11, 期 10, 页码 4456-4461出版社
AMER CHEMICAL SOC
DOI: 10.1021/nl202761g
关键词
Quantum dots; exonuclease; sensor; DNA; multiplexed analysis; FRET
类别
资金
- EU
Quantum dots (QDs) functionalized with a black-hole quencher are used as optical tracer for the detection of DNA using exonuclease as a biocatalyst. The binding of the target DNA or of a target/open hairpin complex to the functionalized QDs leads to the exonuclease-stimulated recycling of the target DNA or the target/hairpin complex. This results in the triggering of the luminescence of the QDs that provides a readout signal for the amplified sensing process. By using different-sized QDs, the multiplexed detection of DNAs is demonstrated.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据