期刊
SENSORS AND ACTUATORS B-CHEMICAL
卷 221, 期 -, 页码 586-592出版社
ELSEVIER SCIENCE SA
DOI: 10.1016/j.snb.2015.07.008
关键词
Ratiometric fluorescent nanosensor; Carbon dots; 5'-Guanosine monophosphate disodium; 2,6-Pyridinedicarboxylic acid; Europium-based nanoscale coordination polymers
资金
- National Natural Science Foundation of China [21165010, 21465014, 21465015]
- Natural Science Foundation of Jiangxi Province [20142BAB203101, 20143ACB21016]
- Ministry of Education by Specialized Research Fund for the Doctoral Program of Higher Education [20133604110002]
- Ground Plan of Science and Technology Projects of Jiangxi Educational Committee [KJLD14023]
- Open Project Program of Key Laboratory of Functional Small Organic Molecule, Ministry of Education, Jiangxi Normal University [KLFS-KF-201410, KLFS-KF-201416]
A ratiometric fluorescent nanosensor for biological warfare agent 2,6-pyridinedicarboxylic acid (DPA) detection is developed with carbon dots (CDs)@europium-based nanoscale coordination polymers (Eu-NCPs). The abundant hydroxyl and carboxyl groups of CDs are served as starting points for the spontaneous self-assembly of europium ion (Eu3+) and 5'-guanosine monophosphate disodium (GMP) on the surface of CDs to form CDs@Eu/GMP nanocomposites. The obtained nanosensor exhibits the characteristic emission of CDs and weak emission of Eu3+. The Eu/GMP NCPs are served as the DPA recognition sites. The fluorescence of CDs remains constant as a reference, while the fluorescence of Eu/GMP NCPs is enhanced upon binding with DPA, resulting in ratiometric fluorescent response toward DPA. This ratiometric nanosensor exhibits good selectivity toward DPA detection. The ratio of F-615/F-469 linearly increases with the increasing of DPA concentration in the range of 25 nM-5.0 mu M with a detection limit as low as 5.1 nM. Additionally, the nanosensor is successfully applied for the determination of DPA in the real serum samples. (C) 2015 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据