期刊
MYCOSES
卷 56, 期 2, 页码 101-104出版社
WILEY
DOI: 10.1111/j.1439-0507.2012.02210.x
关键词
1; 3--D-glucan; bacteraemia; haematological malignancy
资金
- Ministry of Health of the Czech Republic [IGA NS10442-3/2009, IGA NS10441-3/2009]
- Ministry of Education, Youth, and Sports of the Czech Republic [MSM6198959223]
There are discrepancies in the retrospective studies published in literature of whether or not bacteraemia could lead to false positivity of 1,3--D (BG) glucan assay. We performed, for the first time, a prospective study evaluating the role of bacterial bloodstream infection to the reactivity of BG assay. Twenty-six episodes of bacteraemia that occurred in high-risk haematological patients were included in our study. Consecutive BG levels >80pgml1 were required for test positivity. Only 2 of 26 patients were BG positive both with IFDs. Thus, we prospectively did not prove bacteraemia as the source of cross reactivity of BG assay in haematological patients.
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