期刊
MYCOPATHOLOGIA
卷 178, 期 5-6, 页码 427-433出版社
SPRINGER
DOI: 10.1007/s11046-014-9775-z
关键词
Aspergillus; Antifungal resistance; Cryptic species; Antifungal susceptibility testing
类别
资金
- Spanish Network for the Research in Infectious Diseases Instituto de Salud Carlos III [REIPI RD12/0015]
- European Development Regional Fund A way to achieve Europe ERDF
- Spanish Network for the Research in Infectious Diseases [REIPI RD12/0015]
- Fondo de Investigaciones Sanitarias [MPY1369/13]
- Fondo de Investigacion Sanitaria [CP11/00026]
The use of molecular tools has led to the description of new cryptic species among different Aspergillus species complexes. Their frequency in the clinical setting has been reported to be between 10 and 15 %. The susceptibility to azoles and amphotericin B of many of these species is low, and some of them, such as Aspergillus calidoustus or Aspergillus lentulus, are considered multi-resistant. The changing epidemiology, the frequency of cryptic species, and the different susceptibility profiles make antifungal susceptibility testing an important tool to identify the optimal antifungal agent to treat the infections caused by these species.
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