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HFE H63D polymorphism is increased in patients with amyotrophic lateral sclerosis of Italian origin
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JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2007)
Amyotrophic lateral sclerosis 2-deficiency leads to neuronal degeneration in amyotrophic lateral sclerosis through altered AMPA receptor trafficking
Chen Lai et al.
JOURNAL OF NEUROSCIENCE (2006)
Insoluble mutant SOD1 is partly oligoubiquitinated in amyotrophic lateral sclerosis mice
Manuela Basso et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
The epidemiology of ALS and the role of population-based registries
Ettore Beghi et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2006)
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
Manuela Neumann et al.
SCIENCE (2006)
ALS phenotypes with mutations in CHMP2B (charged multivesicular body protein 2B)
N. Parkinson et al.
NEUROLOGY (2006)
Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17
Matt Baker et al.
NATURE (2006)
Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21
Marc Cruts et al.
NATURE (2006)
Lack of association of VEGF promoter polymorphisms with sporadic ALS
W. Chen et al.
NEUROLOGY (2006)
Antisense oligonucleotide therapy for neurodegenerative disease
Richard A. Smith et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Neuroprotective agents for clinical trials in ALS - A systematic assessment
B. J. Traynor et al.
NEUROLOGY (2006)
The first ALS2 missense mutation associated with JPLS reveals new aspects of alsin biological function
Chris Panzeri et al.
BRAIN (2006)
Alsin/Rac1 signaling controls survival and growth of spinal motoneurons
Arnaud Jacquier et al.
ANNALS OF NEUROLOGY (2006)
Trial of celecoxib in amyotrophic lateral sclerosis
Merit E. Cudkowicz et al.
ANNALS OF NEUROLOGY (2006)
Randomized controlled phase II trial of glatiramer acetate in ALS
PH Gordon et al.
NEUROLOGY (2006)
ANG mutations segregate with familial and 'sporadic' amyotrophic lateral sclerosis
MJ Greenway et al.
NATURE GENETICS (2006)
Axonal damage markers in cerebrospinal fluid are increased in ALS
J Brettschneider et al.
NEUROLOGY (2006)
Pentoxifylline in ALS - A double-blind, randomized, multicenter, placebo-controlled trial
V Meininger et al.
NEUROLOGY (2006)
Beneficial effects of intrathecal IGF-1 administration in patients with amyotrophic lateral sclerosis
I Nagano et al.
NEUROLOGICAL RESEARCH (2005)
Association of the H63D polymorphism in the hemochromatosis gene with sporadic ALS
EF Goodall et al.
NEUROLOGY (2005)
Prevalence and patterns of cognitive impairment in sporadic ALS
GM Ringholz et al.
NEUROLOGY (2005)
Aberrant morphology and residual transmitter release at the Munc13-deficient mouse neuromuscular synapse
F Varoqueaux et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
High dose vitamin E therapy in amyotrophic lateral sclerosis as add-on therapy to riluzole: results of a placebo-controlled double-blind study
M Graf et al.
JOURNAL OF NEURAL TRANSMISSION (2005)
A pilot, double-blind, placebo-controlled trial of indinavir in patients with ALS
SN Scelsa et al.
NEUROLOGY (2005)
Alsin, the product of ALS2 gene, suppresses SOD1 mutant neurotoxicity through RhoGEF domain by interacting with SOD1 mutants
K Kanekura et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Increased incidence of the Hfe mutation in amyotrophic lateral sclerosis and related cellular consequences
XS Wang et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2004)
A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis
AL Nishimura et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2004)
Efficacy and safety of xaliproden in amyotrophic lateral sclerosis: results of two phase III trials
V Meininger et al.
AMYOTROPHIC LATERAL SCLEROSIS (2004)
Xaliproden in amyotrophic lateral sclerosis: early clinical trials
L Lacomblez et al.
AMYOTROPHIC LATERAL SCLEROSIS (2004)
DNA/RNA helicase gene mutations in a form of juvenile amyotrophic lateral sclerosis (ALS4)
YZ Chen et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2004)
Placebo-controlled phase I/II studies of minocycline in amyotrophic lateral sclerosis
PH Gordon et al.
NEUROLOGY (2004)
HFE mutations are not strongly associated with sporadic ALS
AA Yen et al.
NEUROLOGY (2004)
Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice
AM Clement et al.
SCIENCE (2003)
Progranulin (granulin-epithelin precursor, PC-cell-derived growth factor, acrogranin) mediates tissue repair and tumorigenesis
ZH He et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2003)
A randomized, placebo-controlled trial of topiramate in amyotrophic lateral sclerosis
ME Cudkowicz et al.
NEUROLOGY (2003)
VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death
D Lambrechts et al.
NATURE GENETICS (2003)
A double-blind randomized clinical trial in amyotrophic lateral sclerosis using lamotrigine: effects on CSF glutamate, aspartate, branched-chain amino acid levels and clinical parameters
H Ryberg et al.
ACTA NEUROLOGICA SCANDINAVICA (2003)
A randomized sequential trial of creatine in amyotrophic lateral sclerosis
GJ Groeneveld et al.
ANNALS OF NEUROLOGY (2003)
Genetic epidemiology of amyotrophic lateral sclerosis
D Majoor-Krakauer et al.
CLINICAL GENETICS (2003)
Oxidation-induced misfolding and agagaregation of superoxide dismutase and its implications for amyotrophic lateral sclerosis
R Rakhit et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
True sporadic ALS associated with a novel SOD-1 mutation
MD Alexander et al.
ANNALS OF NEUROLOGY (2002)
A study of riluzole in the treatment of advanced stage or elderly patients with amyotrophic lateral sclerosis
G Bensimon et al.
JOURNAL OF NEUROLOGY (2002)
The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis
Y Yang et al.
NATURE GENETICS (2001)
Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration
B Oosthuyse et al.
NATURE GENETICS (2001)
Phase III randomized trial of gabapentin in patients with amyotrophic lateral sclerosis
RG Miller et al.
NEUROLOGY (2001)
A double-blind, placebo-controlled randomized clinical trial of α-tocopherol (vitamin E) in the treatment of amyotrophic lateral sclerosis
C Desnuelle et al.
AMYOTROPHIC LATERAL SCLEROSIS (2001)
El Escorial revisited: Revised criteria for the diagnosis of amyotrophic lateral sclerosis
BR Brooks et al.
AMYOTROPHIC LATERAL SCLEROSIS AND OTHER MOTOR NEURON DISORDERS (2000)
Clinical features of amyotrophic lateral sclerosis according to the El Escorial and Airlie House diagnostic criteria -: A population-based study
BJ Traynor et al.
ARCHIVES OF NEUROLOGY (2000)
A phase I/II trial of recombinant methionyl human brain derived neurotrophic factor administered by intrathecal infusion to patients with amyotrophic lateral sclerosis
G Ochs et al.
AMYOTROPHIC LATERAL SCLEROSIS AND OTHER MOTOR NEURON DISORDERS (2000)
Geography of HFE C282Y and H63D mutations
AT Merryweather-Clarke et al.
GENETIC TESTING (2000)
A randomized controlled trial of recombinant interferon beta-1a in ALS
E Beghi et al.
NEUROLOGY (2000)
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