Organic nanoparticles for drug delivery and imaging

Nanotechnology has had a huge impact on the development of therapeutics over the last couple of decades. To date, a large number of organic nanoparticles have been developed to encapsulate and deliver therapeutic and imaging agents. These nanoparticles have allowed encapsulation and targeted release of drugs. A few nanoparticle-based drugs are already being used in patients, and several others are making excellent progress toward clinical translation. The strong pipeline of therapeutic nanoparticles is fueled by advances in novel materials and design features, new applications, and a better understanding of fundamental hurdles that limit the utility of nanoparticles. The articles in this issue of MRS Bulletin are focused on some of the significant recent advances in the use of organic nanoparticles for drug delivery and imaging.