期刊
MOVEMENT DISORDERS
卷 27, 期 3, 页码 349-356出版社
WILEY
DOI: 10.1002/mds.24893
关键词
Parkinson's disease; cognition; mild cognitive impairment; diagnostic criteria; dementia
资金
- Medtronic
- GlaxoSmithKline
- National Parkinson Foundation
- National Institutes of Health [P50 AG016574, U01 AG006786, NS36630, RR024156]
- Parkinson's UK
- European Union
- Child Health and Development Institute
- Michael J. Fox Foundation for Parkinson's Research
- Teva Lundbeck
- Springer
- MRC [G0800784] Funding Source: UKRI
- Medical Research Council [G0800784, G0800784B] Funding Source: researchfish
Mild cognitive impairment is common in nondemented Parkinson's disease (PD) patients and may be a harbinger of dementia. In view of its importance, the Movement Disorder Society commissioned a task force to delineate diagnostic criteria for mild cognitive impairment in PD. The proposed diagnostic criteria are based on a literature review and expert consensus. This article provides guidelines to characterize the clinical syndrome and methods for its diagnosis. The criteria will require validation, and possibly refinement, as additional research improves our understanding of the epidemiology, presentation, neurobiology, assessment, and long-term course of this clinical syndrome. These diagnostic criteria will support future research efforts to identify at the earliest stage those PD patients at increased risk of progressive cognitive decline and dementia who may benefit from clinical interventions at a predementia stage. (c) 2012 Movement Disorder Society
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