期刊
MOVEMENT DISORDERS
卷 24, 期 1, 页码 15-24出版社
WILEY
DOI: 10.1002/mds.22378
关键词
Tourette's syndrome; tics; ADHD; OCD
资金
- NINDS NIH HHS [T32 NS007338, T32 NS007338-19] Funding Source: Medline
A tic is a stereotyped repetitive involuntary movement or sound, frequently preceded by premonitory sensations or Urges. Most tic disorders are genetic or idiopathic in nature, possibly due to a developmental failure of inhibitory function Within frontal-subcortical circuits modulating volitional movements. Currently available oral medications can reduce the severity of tics, but rarely eliminate them. Botulinum toxin injections can be effective if there are it few particularly disabling motor tics. Deep brain stimulation has been reported to be an effective treatment for the most severe cases, but remains unproven. A comprehensive evaluation accounting For secondary causes, psychosocial factors. and comorbid neuropsychiatric conditions is essential to successful treatment of tic disorders. (c) 2009 Movement Disorder Society
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