相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Deep Brain Stimulation for Parkinson Disease An Expert Consensus and Review of Key Issues
Jeff M. Bronstein et al.
ARCHIVES OF NEUROLOGY (2011)
Cell-based Therapeutic Approaches for Parkinson's Disease: Progress and Perspectives
S.V. Anisimov
REVIEWS IN THE NEUROSCIENCES (2011)
Potential cellular and regenerative approaches for the treatment of Parkinson’s disease
Emma Lane et al.
Neuropsychiatric Disease and Treatment (2011)
Lewy body pathology in fetal grafts
Yaping Chu et al.
YEAR IN NEUROLOGY 2 (2010)
The A9 dopamine neuron component in grafts of ventral mesencephalon is an important determinant for recovery of motor function in a rat model of Parkinson's disease
Shane Grealish et al.
BRAIN (2010)
被撤回的出版物: Efficient Derivation of Functional Floor Plate Tissue from Human Embryonic Stem Cells (Retracted article. See vol. 30, pg. 905, 2023)
Christopher A. Fasano et al.
CELL STEM CELL (2010)
Patient-Specific Pluripotent Stem Cells Become Even More Accessible
Shinya Yamanaka
CELL STEM CELL (2010)
Induction of pluripotency by defined factors
Keisuke Okita et al.
EXPERIMENTAL CELL RESEARCH (2010)
Preclinical Assessment of Stem Cell Therapies for Neurological Diseases
Valerie L. Joers et al.
ILAR JOURNAL (2010)
Stem cells in human neurodegenerative disorders - time for clinical translation?
Olle Lindvall et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Differentiation of human ES and Parkinson's disease iPS cells into ventral midbrain dopaminergic neurons requires a high activity form of SHH, FGF8a and specific regionalization by retinoic acid
Oliver Cooper et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2010)
Gene Therapy for Parkinson's Disease
Tomas Bjorklund et al.
MOVEMENT DISORDERS (2010)
Characterization of Lewy Body Pathology in 12-and 16-Year-Old Intrastriatal Mesencephalic Grafts Surviving in a Patient With Parkinson's Disease
Jia-Yi Li et al.
MOVEMENT DISORDERS (2010)
Role of Serotonin Neurons in the Induction of Levodopa- and Graft-Induced Dyskinesias in Parkinson's Disease
Manolo Carta et al.
MOVEMENT DISORDERS (2010)
Epigenetic memory in induced pluripotent stem cells
K. Kim et al.
NATURE (2010)
Nuclear reprogramming to a pluripotent state by three approaches
Shinya Yamanaka et al.
NATURE (2010)
Direct conversion of fibroblasts to functional neurons by defined factors
Thomas Vierbuchen et al.
NATURE (2010)
Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells
Jose M. Polo et al.
NATURE BIOTECHNOLOGY (2010)
Induced pluripotent stem cell technology for the study of human disease
Gabsang Lee et al.
NATURE METHODS (2010)
Generation of mouse-induced pluripotent stem cells with plasmid vectors
Keisuke Okita et al.
NATURE PROTOCOLS (2010)
Prion-like transmission of protein aggregates in neurodegenerative diseases
Patrik Brundin et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
DIFFERENTIATION OF NON-MESENCEPHALIC NEURAL STEM CELLS TOWARDS DOPAMINERGIC NEURONS
R. Rossler et al.
NEUROSCIENCE (2010)
Stem cell-derived dopamine neurons for brain repair in Parkinson's disease
Rosemary A. Fricker-Gates et al.
REGENERATIVE MEDICINE (2010)
Cellular Repair in the Parkinsonian Nonhuman Primate Brain
Donald Eugene Redmond et al.
REJUVENATION RESEARCH (2010)
Serotonergic Neurons Mediate Dyskinesia Side Effects in Parkinson's Patients with Neural Transplants
Marios Politis et al.
SCIENCE TRANSLATIONAL MEDICINE (2010)
Human Induced Pluripotent Stem Cells Develop Teratoma More Efficiently and Faster Than Human Embryonic Stem Cells Regardless the Site of Injection
Ivan Gutierrez-Aranda et al.
STEM CELLS (2010)
The propagation of prion-like protein inclusions in neurodegenerative diseases
Michel Goedert et al.
TRENDS IN NEUROSCIENCES (2010)
Staging/typing of Lewy body related α-synuclein pathology: a study of the BrainNet Europe Consortium
Irina Alafuzoff et al.
ACTA NEUROPATHOLOGICA (2009)
Dopaminergic Transplantation for Parkinson's Disease: Current Status and Future Prospects
C. Warren Olanow et al.
ANNALS OF NEUROLOGY (2009)
Parkinson's Disease The Dual Hit Theory Revisited
Christopher H. Hawkes et al.
INTERNATIONAL SYMPOSIUM ON OLFACTION AND TASTE (2009)
Cell-Based Therapies for Parkinson's Disease: Past, Present, and Future
Kathleen M. Fitzpatrick et al.
ANTIOXIDANTS & REDOX SIGNALING (2009)
Scientific rationale for the development of gene therapy strategies for Parkinson's disease
Tomas Bjorklund et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2009)
Cell replacement therapy for Parkinson's disease
Ruwani Wijeyekoon et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2009)
Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors
Frank Soldner et al.
CELL (2009)
Gene Therapy for Neurological Disorders: Challenges and Future Prospects for the Use of Growth Factors for the Treatment of Parkinson's Disease
Fredric P. Manfredsson et al.
CURRENT GENE THERAPY (2009)
Cell-based therapies in Parkinson's disease
Paul Greene
CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS (2009)
Coordination of sonic hedgehog and Wnt signaling determines ventral and dorsal telencephalic neuron types from human embryonic stem cells
Xue-Jun Li et al.
DEVELOPMENT (2009)
Reconstruction of the nigrostriatal dopamine pathway in the adult mouse brain
Lachlan H. Thompson et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2009)
Propagation of host disease to grafted neurons: Accumulating evidence
Jeffrey H. Kordower et al.
EXPERIMENTAL NEUROLOGY (2009)
Embryonic Substantia Nigra Grafts in the Mesencephalon Send Neurites to the Host Striatum in Non-Human Primate After Overexpression of GDNF
D. E. Redmond et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2009)
Neuronal cell replacement in Parkinson's disease
E. Hedlund et al.
JOURNAL OF INTERNAL MEDICINE (2009)
Lack of functional relevance of isolated cell damage in transplants of Parkinson's disease patients
Oliver Cooper et al.
JOURNAL OF NEUROLOGY (2009)
Formation and development of Lewy pathology: a critical update
Kurt A. Jellinger
JOURNAL OF NEUROLOGY (2009)
Positron Emission Tomography Imaging Demonstrates Correlation between Behavioral Recovery and Correction of Dopamine Neurotransmission after Gene Therapy
Ludovic Leriche et al.
JOURNAL OF NEUROSCIENCE (2009)
Tight Long-term Dynamic Doxycycline Responsive Nigrostriatal GDNF Using a Single rAAV Vector
Fredric P. Manfredsson et al.
MOLECULAR THERAPY (2009)
Clinical Pattern and Risk Factors for Dyskinesias Following Fetal Nigral Transplantation in Parkinson's Disease: A Double Blind Video-Based Analysis
C. Warren Olanow et al.
MOVEMENT DISORDERS (2009)
Virus-free induction of pluripotency and subsequent excision of reprogramming factors
Keisuke Kaji et al.
NATURE (2009)
Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling
Stuart M. Chambers et al.
NATURE BIOTECHNOLOGY (2009)
Medical records documentation of constipation preceding Parkinson disease A case-control study
R. Savica et al.
NEUROLOGY (2009)
Lewy body pathology in long-term fetal nigral transplants: is Parkinson's disease transmitted from one neural system to another?
Jeffrey H. Kordower et al.
NEUROPSYCHOPHARMACOLOGY (2009)
EXPRESSION, BIOACTIVITY, AND SAFETY 1 YEAR AFTER ADENO-ASSOCIATED VIRAL VECTOR TYPE 2-MEDIATED DELIVERY OF NEURTURIN TO THE MONKEY NIGROSTRIATAL SYSTEM SUPPORT CERE-120 FOR PARKINSON'S DISEASE
Christopher D. Herzo et al.
NEUROSURGERY (2009)
Inclusion formation and neuronal cell death through neuron-to-neuron transmission of α-synuclein
Paula Desplats et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Efficient production of mesencephalic dopamine neurons by Lmx1a expression in embryonic stem cells
Stina Friling et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Is Parkinson's disease a prion disorder?
C. Warren Olanow et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
NEUROSCIENCE Fetal Cells Again?
Constance Holden
SCIENCE (2009)
Cell Therapy Ahead for Parkinson's Disease
Ole Isacson
SCIENCE (2009)
Dopamine Gene Therapy for Parkinson's Disease in a Nonhuman Primate Without Associated Dyskinesia
Bechir Jarraya et al.
SCIENCE TRANSLATIONAL MEDICINE (2009)
Gene Therapy for Dopamine Replacement in Parkinson's Disease
Anders Bjorklund et al.
SCIENCE TRANSLATIONAL MEDICINE (2009)
The Role of Lmx1a in the Differentiation of Human Embryonic Stem Cells into Midbrain Dopamine Neurons in Culture and After Transplantation into a Parkinson's Disease Model
Jingli Cai et al.
STEM CELLS (2009)
Prospects of stem cell therapy for replacing dopamine neurons in Parkinson's disease
Olle Lindvall et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2009)
One year survival and significant reversal of motor deficits in parkinsonian rats transplanted with hESC derived dopaminergic neurons
Geeta Ravindran et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
A multitarget basal ganglia dopaminergic and GABAergic transplantation strategy enhances behavioural recovery in parkinsonian rats
K. Mukhida et al.
BRAIN (2008)
Parthenogenetic dopamine neurons from primate embryonic stem cells restore function in experimental Parkinsons disease
Rosario Sanchez-Pernaute et al.
BRAIN (2008)
Disease-specific induced pluripotent stem cells
In-Hyun Park et al.
CELL (2008)
Guidelines and Techniques for the Generation of Induced Pluripotent Stem Cells
Nimet Maherali et al.
CELL STEM CELL (2008)
A high-efficiency system for the generation and study of human induced pluripotent stem cells
Nimet Maherali et al.
CELL STEM CELL (2008)
Applications of Lentiviral Vectors for Biology and Gene Therapy of Neurological Disorders
Cecilia Lundberg et al.
CURRENT GENE THERAPY (2008)
Potentials of ES Cell Therapy in Neurodegenerative Diseases
Anand S. Srivastava et al.
CURRENT PHARMACEUTICAL DESIGN (2008)
Current status of gene therapy trials for Parkinson's disease
Massimo Fiandaca et al.
EXPERIMENTAL NEUROLOGY (2008)
AAV2-mediated gene transfer of GDNF to the striatum of MPTP monkeys enhances the survival and outgrowth of co-implanted fetal dopamine neurons
J. D. Elsworth et al.
EXPERIMENTAL NEUROLOGY (2008)
Non-dopaminergic neurons in ventral mesencephalic transplants make widespread axonal connections in the host brain
Lachlan H. Thompson et al.
EXPERIMENTAL NEUROLOGY (2008)
Preclinical development of gene therapy for Parkinson's disease
Gregory Porras et al.
EXPERIMENTAL NEUROLOGY (2008)
Viral vectors for in vivo gene transfer in Parkinson's disease: Properties and clinical grade production
Ronald J. Mandel et al.
EXPERIMENTAL NEUROLOGY (2008)
Design of clinical trials of gene therapy in Parkinson disease
Travis B. Lewis et al.
EXPERIMENTAL NEUROLOGY (2008)
The need for regulatable vectors for gene therapy for Parkinson's disease
Dean E. Cress
EXPERIMENTAL NEUROLOGY (2008)
Regulatable promoters and gene therapy for Parkinson's disease: Is the only thing to fear, fear itself?
Jeffrey H. Kordower et al.
EXPERIMENTAL NEUROLOGY (2008)
Human neural progenitor cells over-expressing IGF-1 protect dopamine neurons and restore function in a rat model of Parkinson's disease
Allison D. Ebert et al.
EXPERIMENTAL NEUROLOGY (2008)
Human neural stem cells migrate along the nigrostriatal pathway in a primate model of Parkinson's disease
Kimberly B. Bjugstad et al.
EXPERIMENTAL NEUROLOGY (2008)
Neurotrophic factors as a therapeutic target for Parkinson's disease
Jonathan R. Evans et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2008)
GDNF therapy for Parkinson’s disease
Murray Hong et al.
Expert Review of Neurotherapeutics (2008)
Immunity to adeno-associated virus vectors in animals and humans: a continued challenge
A. K. Zaiss et al.
GENE THERAPY (2008)
Safety and tolerability of intraputaminal delivery of CERE-120 (adeno-associated virus serotype 2-neurturin) to patients with idiopathic Parkinson's disease: an open-label, phase I trial
William J. Marks et al.
LANCET NEUROLOGY (2008)
Transgene expression, bioactivity, and safety of CERE-120 (AAV2-neurturin) following delivery to the monkey striatum
Christopher D. Herzog et al.
MOLECULAR THERAPY (2008)
Placebo response in Parkinson's disease: Comparisons among 11 trials covering medical and surgical interventions
Christopher G. Goetz et al.
MOVEMENT DISORDERS (2008)
Placebo influences on dyskinesia in Parkinson's disease
Christopher G. Goetz et al.
MOVEMENT DISORDERS (2008)
Transplanted Dopaminergic Neurons Develop PD Pathologic Changes: A Second Case Report
Jeffrey H. Kordower et al.
MOVEMENT DISORDERS (2008)
The Prodromal Phase of Sporadic Parkinson's Disease: Does It Exist and If So How Long Is It?
Christopher H. Hawkes
MOVEMENT DISORDERS (2008)
Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2
Danwei Huangfu et al.
NATURE BIOTECHNOLOGY (2008)
Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation
Jia-Yi Li et al.
NATURE MEDICINE (2008)
Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease
Jeffrey H. Kordower et al.
NATURE MEDICINE (2008)
Absolute requirement of GDNF for adult catecholaminergic neuron survival
Alberto Pascual et al.
NATURE NEUROSCIENCE (2008)
Efficient derivation of functional dopaminergic neurons from human embryonic stem cells on a large scale
Myung-Soo Cho et al.
NATURE PROTOCOLS (2008)
Generation of human-induced pluripotent stem cells
In-Hyun Park et al.
NATURE PROTOCOLS (2008)
Research in motion: the enigma of Parkinson's disease pathology spread
Patrik Brundin et al.
NATURE REVIEWS NEUROSCIENCE (2008)
Influence of cell preparation and target location on the behavioral recovery after striatal transplantation of fetal dopaminergic neurons in a primate model of Parkinson's disease
D. E. Redmond et al.
NEUROBIOLOGY OF DISEASE (2008)
Results from a phase I safety trial of hAADC gene therapy for Parkinson disease
J. L. Eberling et al.
NEUROLOGY (2008)
Differentiation of neural lineage cells from human pluripotent stem cells
Philip H. Schwartz et al.
METHODS (2008)
GENE AND CELL DELIVERY TO THE DEGENERATED STRIATUM: STATUS OF PRECLINICAL EFFORTS IN PRIMATE MODELS
R. Mark Richardson et al.
NEUROSURGERY (2008)
Recent advances in cell-based therapy for Parkinson disease
Arnar Astradsson et al.
NEUROSURGICAL FOCUS (2008)
Treatment of Parkinson's disease with trophic factors
Amie L. Peterson et al.
NEUROTHERAPEUTICS (2008)
Therapeutic Potentials of human embryonic stem cells in Parkinson's disease
Mary B. Newman et al.
NEUROTHERAPEUTICS (2008)
Involvement of the serotonin system in l-dopa-induced dyskinesias
Manolo Carta et al.
PARKINSONISM & RELATED DISORDERS (2008)
Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease
Marius Wernig et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Induced Pluripotent Stem Cells Generated Without Viral Integration
Matthias Stadtfeld et al.
SCIENCE (2008)
Generation of Mouse Induced Pluripotent Stem Cells Without Viral Vectors
Keisuke Okita et al.
SCIENCE (2008)
Directed differentiation of ventral spinal progenitors and motor neurons from human embryonic stem cells by small molecules
Xue-Jun Li et al.
STEM CELLS (2008)
Noggin Enhances Dopamine Neuron Production from Human Embryonic Stem Cells and Improves Behavioral Outcome After Transplantation into Parkinsonian Rats
Shunmei Chiba et al.
STEM CELLS (2008)
Embryonic stem cell-derived Pitx3-enhanced green fluorescent protein midbrain dopamine neurons survive enrichment by fluorescence-activated cell sorting and function in an animal model of Parkinson's disease
Eva Hedlund et al.
STEM CELLS (2008)
Human embryonic stem cell-derived dopaminergic neurons reverse functional deficit in Parkinsonian rats
Dali Yang et al.
STEM CELLS (2008)
GDNF and GFRα:: a versatile molecular complex for developing neurons
Gustavo Paratcha et al.
TRENDS IN NEUROSCIENCES (2008)
Is deep brain stimulation neuroprotective if applied early in the course of PD?
P. David Charles et al.
NATURE CLINICAL PRACTICE NEUROLOGY (2008)
Growth factors and feeder cells promote differentiation of human embryonic stem cells into dopaminergic neurons: a novel role for fibroblast growth factor-20
Ana Sofia Correia et al.
FRONTIERS IN NEUROSCIENCE (2008)
Reprogramming of human somatic cells to pluripotency with defined factors
In-Hyun Park et al.
NATURE (2008)
Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts
Masato Nakagawa et al.
NATURE BIOTECHNOLOGY (2008)
Human stem cells for CNS repair
Rike Zietlow et al.
CELL AND TISSUE RESEARCH (2008)
From bench to bed: the potential of stem cells for the treatment of Parkinson's disease
Asuka Morizane et al.
CELL AND TISSUE RESEARCH (2008)
Parkinson's disease: a dual-hit hypothesis
C. H. Hawkes et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2007)
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
Kazutoshi Takahashi et al.
CELL (2007)
Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells
Alexander Meissner et al.
NATURE BIOTECHNOLOGY (2007)
The future of cell therapies in the treatment of Parkinson's disease
Rocio Laguna Goy et al.
EXPERT OPINION ON BIOLOGICAL THERAPY (2007)
Long-term survival of encapsulated GDNF secreting cells implanted within the striatum of parkinsonized rats
Laura Grandoso et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2007)
Markers and methods for cell sorting of human embryonic stem cell-derived neural cell Populations
Jan Pruszak et al.
STEM CELLS (2007)
Lentiviral vector-mediated genetic modification of human neural progenitor cells for ex vivo gene therapy
Elizabeth E. Capowski et al.
JOURNAL OF NEUROSCIENCE METHODS (2007)
Serotonin neuron transplants exacerbate L-DOPA-induced dyskinesias in a rat model of Parkinson's disease
Thomas Carlsson et al.
JOURNAL OF NEUROSCIENCE (2007)
In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state
Marius Wernig et al.
NATURE (2007)
Behavioral improvement in a primate Parkinson's model is associated with multiple homeostatic effects of human neural stem cells
D. Eugene Redmond et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Strategies and new developments in the generation of patient-specific pluripotent stem cells
Shinya Yamanaka
CELL STEM CELL (2007)
Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution
Nimet Maherali et al.
CELL STEM CELL (2007)
Cell-replacement and gene-therapy strategies for Parkinson's and Alzheimer's disease
Joanna A. Korecka et al.
REGENERATIVE MEDICINE (2007)
AAV2 - mediated delivery of human neurturin to the rat nigrostriatal system: Long-term efficacy and tolerability of CERE-120 for Parkinson's disease
Mehdi Gasmi et al.
NEUROBIOLOGY OF DISEASE (2007)
Dopamine released from 5-HT terminals is the cause of L-DOPA-induced dyskinesia in Parkinsonian rats
Manolo Carta et al.
BRAIN (2007)
Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: an open label, phase I trial
Michael G. Kaplitt et al.
LANCET (2007)
Striatal delivery of CERE-120, an AAV2 vector encoding human neurturin, enhances activity of the dopaminergic nigrostriatal system in aged monkeys
Christopher D. Herzog et al.
MOVEMENT DISORDERS (2007)
Directed neural differentiation of human embryonic stem cells via an obligated primitive anterior stage
Matthew T. Pankratz et al.
STEM CELLS (2007)
Dopamine neuron systems in the brain:: an update
Anders Bjorklund et al.
TRENDS IN NEUROSCIENCES (2007)
Unilateral intraputamenal glial cell line-derived neurotrophic factor in patients with Parkinson disease: response to 1 year of treatment and 1 year of withdrawal
John T. Slevin et al.
JOURNAL OF NEUROSURGERY (2007)
Subthalamic glutamic acid decarboxylase gene therapy: changes in motor function and cortical metabolism
Marina E. Emborg et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2007)
Benefits, risks and ethical considerations in translation of stem cell research to clinical applications in Parkinson's disease
Zubin Master et al.
JOURNAL OF MEDICAL ETHICS (2007)
Enhanced yield of neuroepithelial precursors and midbrain-like dopaminergic neurons from human embryonic stem cells using the bone morphogenic protein antagonist Noggin
Kai-Christian Sonntag et al.
STEM CELLS (2007)
A protocol for the differentiation of human embryonic stem cells into dopaminergic neurons using only chemically defined human additives: Studies in vitro and in vivo
Lorraine Iacovitti et al.
BRAIN RESEARCH (2007)
Issues regarding gene therapy products for Parkinson's disease: The development of CERE-120 (AAV-NTN) as one reference point
Raymond T. Bartus et al.
PARKINSONISM & RELATED DISORDERS (2007)
Striatal delivery of neurturin by CERE-120, an AAV2 vector for the treatment of dopaminergic neuron degeneration in Parkinson's disease
Mehdi Gasmi et al.
MOLECULAR THERAPY (2007)
Induction of pluripotent stem cells from fibroblast cultures
Kazutoshi Takahashi et al.
NATURE PROTOCOLS (2007)
Persistent dopamine functions of neurons derived from embryonic stem cells in a rodent model of Parkinson disease
Jose A. Rodriguez-Gomez et al.
STEM CELLS (2007)
Selection of embryonic stem cell-derived enhanced green fluorescent protein-positive dopamine neurons using the tyrosine hydroxylase promoter is confounded by reporter gene expression in immature cell populations
Eva Hedlund et al.
STEM CELLS (2007)
Nonhuman primate models of Parkinson's disease
Marina E. Emborg
ILAR JOURNAL (2007)
Restoration of the striatal dopamine synthesis for Parkinson's disease: Viral vector-mediated enzyme replacement strategy
Thomas Carlsson et al.
CURRENT GENE THERAPY (2007)
Translational considerations for CNS gene therapy
Deborah A. Ryan et al.
EXPERT OPINION ON BIOLOGICAL THERAPY (2007)
Tyrosine hydroxylase expression is unstable in a human immortalized mesencephalic cell line - Studies in vitro and after intracerebral grafting in vivo
Gesine Paul et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2007)
Six-month continuous intraputamenal infusion toxicity study of recombinant methionyl human glial cell line-derived neurotrophic factor (r-metHuGDNF) in rhesus monkeys
David N. Hovland et al.
TOXICOLOGIC PATHOLOGY (2007)
The importance of A9 dopaminergic neurons in mediating the functional benefits of fetal ventral mesencephalon transplants and levodopa-induced dyskinesias
Wei-Li Kuan et al.
NEUROBIOLOGY OF DISEASE (2007)
Parkinson's disease: lesions in dorsal horn layer I, involvement of parasympathetic and sympathetic pre- and postganglionic neurons
Heiko Braak et al.
ACTA NEUROPATHOLOGICA (2007)
TCH346 as a neuroprotective drug in Parkinsons disease: a double-blind, randomised, controlled trial
C. Warren Olanow et al.
LANCET NEUROLOGY (2006)
Delivery of neurturin by AAV2 (CERE-120)-mediated gene transfer provides structural and functional neuroprotection and neurorestoration in MPTP-treated monkeys
Jeffrey H. Kordower et al.
ANNALS OF NEUROLOGY (2006)
Human fetal cortical and striatal neural stem cells generate region-specific neurons in vitro and differentiate extensively to neurons after intrastriatal transplantation in neonatal rats
Therese Kallur et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2006)
Stanley Fahn Lecture 2005:: The staging procedure for the inclusion body pathology associated with sporadic Parkinson's disease reconsidered
Heiko Braak et al.
MOVEMENT DISORDERS (2006)
Functional engraftment of human ES cell-derived dopaminergic neurons enriched by coculture with telomerase-immortalized midbrain astrocytes
Neeta S. Roy et al.
NATURE MEDICINE (2006)
Induction of dopaminergic neurons from growth factor expanded neural stem/progenitor cell cultures derived from human first trimester forebrain
Nicolaj S. Christophersen et al.
BRAIN RESEARCH BULLETIN (2006)
Long-term clinical improvement in MPTP-lesioned primates after gene therapy with AAV-hAADC
Krystof S. Bankiewicz et al.
MOLECULAR THERAPY (2006)
A dose-ranging study of AAV-hAADC therapy in parkinsonian monkeys
John R. Forsayeth et al.
MOLECULAR THERAPY (2006)
Transplanted dopamine neurons derived from primate ES cells preferentially innervate DARPP-32 striatal progenitors within the graft
Daniela Ferrari et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2006)
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
Kazutoshi Takahashi et al.
CELL (2006)
Continuous dopamine-receptor treatment of Parkinson's disease: scientific rationale and clinical implications
C. Warren Olanow et al.
LANCET NEUROLOGY (2006)
Human progenitor cells isolated from the developing cortex undergo decreased neurogenesis and eventual senescence following expansion in vitro
Lynda S. Wright et al.
EXPERIMENTAL CELL RESEARCH (2006)
Drug insight: continuous dopaminergic stimulation in the treatment of Parkinson's disease
Warren Olanow et al.
NATURE CLINICAL PRACTICE NEUROLOGY (2006)
Rate of progression determines the clinical outcome after neural transplantation in Parkinson's disease
G Linazasoro
BRAIN (2006)
Transplantation of human embryonic stem cell-derived cells to a rat model of Parkinson's disease: Effect of in vitro differentiation on graft survival and teratoma formation
Anke Brederlau et al.
STEM CELLS (2006)
Gene transfer of trophic factors and stem cell grafting as treatments for Parkinson's disease
Biplob Dass et al.
NEUROLOGY (2006)
Pharmacologic transgene control systems for gene therapy
Wilfried Weber et al.
JOURNAL OF GENE MEDICINE (2006)
Human neurospheres derived from the fetal central nervous system are regionally and temporally specified but are not committed
Young-Tai Kim et al.
EXPERIMENTAL NEUROLOGY (2006)
Neural subtype specification from embryonic stem cells
Su-Chun Zhang
BRAIN PATHOLOGY (2006)
Gastric α-synuclein immunoreactive inclusions in Meissner's and Auerbach's plexuses in cases staged for Parkinson's disease-related brain pathology
H Braak et al.
NEUROSCIENCE LETTERS (2006)
Human neural progenitors deliver glial cell line-derived neurotrophic factor to parkinsonian rodents and aged primates
S Behrstock et al.
GENE THERAPY (2006)
Randomized controlled trial of intraputamenal glial cell line-derived neurotrophic factor infusion in Parkinson disease
AE Lang et al.
ANNALS OF NEUROLOGY (2006)
Lentiviral vectors for use in the central nervous system
J Jakobsson et al.
MOLECULAR THERAPY (2006)
Fluorescence-activated cell sorting-based purification of embryonic stem cell-derived neural precursors averts tumor formation after transplantation
Hitosih Fukuda et al.
STEM CELLS (2006)
Cooperative transcription activation by Nurr1 and Pitx3 induces embryonic stem cell maturation to the midbrain dopamine neuron phenotype
C Martinat et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Crossroads in GDNF therapy for Parkinson's disease
TB Sherer et al.
MOVEMENT DISORDERS (2006)
Developmental perspectives on human midbrain-derived neural stem cells
Johannes Schwarz et al.
NEURODEGENERATIVE DISEASES (2006)
Evolution of the GDNF family ligands and receptors
Matti S. Airaksinen et al.
BRAIN BEHAVIOR AND EVOLUTION (2006)
Neural repair strategies for Parkinson's disease: insights from primate models
Katherine Soderstrom et al.
CELL TRANSPLANTATION (2006)
Cell therapy for Parkinson's disease: Only young onset patients allowed? Reflections about the results of recent clinical trials with cell therapy and the progression of Parkinson's disease
Gurutz Linazasoro
CELL TRANSPLANTATION (2006)
Dyskinesias and dopamine cell replacement in Parkinson's disease: a clinical perspective
P Hagell et al.
BRAIN RESEARCH BULLETIN (2005)
Factors affecting the clinical outcome after neural transplantation in Parkinson's disease
P Piccini et al.
BRAIN (2005)
Lentivector-mediated delivery of GDNF protects complex motor functions relevant to human Parkinsonism in a rat lesion model
E Dowd et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2005)
Regenerative medicine in Parkinson's disease: generation of mesencephalic dopaminergic cells from embryonic stem cells
H Taylor et al.
CURRENT OPINION IN BIOTECHNOLOGY (2005)
Does levodopa slow or hasten the rate of progression of Parkinson's disease?
S Fahn
JOURNAL OF NEUROLOGY (2005)
Efficient in vivo protection of nigral dopaminergic neurons by lentiviral gene transfer of a modified neurturin construct
L Fjord-Larsen et al.
EXPERIMENTAL NEUROLOGY (2005)
Long-term survival of dopamine neurons derived from parthenogenetic primate embryonic stem cells (Cyno-1) after transplantation
R Sánchez-Pernaute et al.
STEM CELLS (2005)
Regulatable gene expression systems for gene therapy applications: Progress and future challenges
S Goverdhana et al.
MOLECULAR THERAPY (2005)
Increased fiber outgrowth from xeno-transplanted human embryonic dopaminergic neurons with co-implants of polymer-encapsulated genetically modified cells releasing glial cell line-derived neurotrophic factor
YH Ahn et al.
BRAIN RESEARCH BULLETIN (2005)
Identification of dopaminergic neurons of nigral and ventral tegmental area subtypes in grafts of fetal ventral mesencephalon based on cell morphology, protein expression, and efferent projections
L Thompson et al.
JOURNAL OF NEUROSCIENCE (2005)
Factors involved in the determination of the neurotransmitter phenotype of developing neurons of the CNS: Applications in cell replacement treatment for Parkinson's disease
SS Riaz et al.
PROGRESS IN NEUROBIOLOGY (2005)
Cell type analysis of functional fetal dopamine cell suspension transplants in the striatum and substantia nigra of patients with Parkinson's disease
I Mendez et al.
BRAIN (2005)
Immune responses to adeno-associated virus vectors
AK Zaiss et al.
CURRENT GENE THERAPY (2005)
Long-term glial cell line-derived neurotrophic factor overexpression in the intact nigrostriatal system in rats leads to a decrease of dopamine and increase of tetrahydrobiopterin production
A Sajadi et al.
JOURNAL OF NEUROCHEMISTRY (2005)
Reversal of dyskinesias in an animal model of Parkinson's disease by continuous L-DOPA delivery using rAAV vectors
T Carlsson et al.
BRAIN (2005)
Improvement of bilateral motor functions in patients with Parkinson disease through the unilateral intraputaminal infusion of glial cell line-derived neurotrophic factor
JT Slevin et al.
JOURNAL OF NEUROSURGERY (2005)
Intraputamenal infusion of glial cell line-derived neurotrophic factor in PD: A two-year outcome study
NK Patel et al.
ANNALS OF NEUROLOGY (2005)
The homeodomain transcription factor Pitx3 facilitates differentiation of mouse embryonic stem cells into AHD2-expressing dopaminergic neurons
S Chung et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2005)
Continuous low-level glial cell line-derived neurotrophic factor delivery using recombinant adeno-associated viral vectors provides neuroprotection and induces behavioral recovery in a primate model of Parkinson's disease
A Eslamboli et al.
JOURNAL OF NEUROSCIENCE (2005)
Neural stem cells implanted into MPTP-treated monkeys increase the size of endogenous tyrosine hydroxylase-positive cells found in the striatum: A return to control measures
KB Bjugstad et al.
CELL TRANSPLANTATION (2005)
Neuroprotection in a rat Parkinson model by GDNF gene therapy using EIAV vector
M Azzouz et al.
NEUROREPORT (2004)
Neuroprotection in Parkinson disease - Mysteries, myths, and misconceptions
AHV Schapira et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2004)
Regulated delivery of glial cell line-derived neurotrophic factor into rat striatum, using a tetracycline-dependent lentiviral vector
B Georgievska et al.
HUMAN GENE THERAPY (2004)
Derivation of midbrain dopamine neurons from human embryonic stem cells
AL Perrier et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Lentiviral vector delivery of parkin prevents dopaminergic degeneration in an α-synuclein rat model of Parkinson's disease
C Lo Bianco et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Overexpression of glial cell line-derived neurotrophic factor using a lentiviral vector induces time-and dose-dependent downregulation of tyrosine hydroxylase in the intact nigrostriatal dopamine system
B Georgievska et al.
JOURNAL OF NEUROSCIENCE (2004)
Lentiviral nigral delivery of GDNF does not prevent neurodegeneration in a genetic rat model of Parkinson's disease
C Lo Bianco et al.
NEUROBIOLOGY OF DISEASE (2004)
Evaluation of animal models of Parkinson's disease for neuroprotective strategies
ME Emborg
JOURNAL OF NEUROSCIENCE METHODS (2004)
The differentiation potential of human foetal neuronal progenitor cells in vitro
SS Riaz et al.
DEVELOPMENTAL BRAIN RESEARCH (2004)
Stages in the development of Parkinson's disease-related pathology
H Braak et al.
CELL AND TISSUE RESEARCH (2004)
Midbrain-derived neural stem cells: from basic science to therapeutic approaches
A Storch et al.
CELL AND TISSUE RESEARCH (2004)
Dopaminergic differentiation of human embryonic stem cells
XM Zeng et al.
STEM CELLS (2004)
Differentiation of human embryonic stem cells to dopaminergic neurons in serum-free suspension culture
TC Schulz et al.
STEM CELLS (2004)
Transplantation of human embryonic stem cell-derived neural progenitors improves behavioral deficit in Parkinsonian rats
T Ben-Hur et al.
STEM CELLS (2004)
Isolation and characterization of neural progenitor cells from post-mortem human cortex
PH Schwartz et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2003)
Recombinant adeno-associated viral vector (rAAV) delivery of GDNF provides protection against 6-OHDA lesion in the common marmoset monkey (Callithrix jacchus)
A Eslamboli et al.
EXPERIMENTAL NEUROLOGY (2003)
Directed neuronal differentiation of human embryonic stem cells
TC Schulz et al.
BMC NEUROSCIENCE (2003)
Functional characterization of dopaminergic neurons derived from rodent mesencephalic progenitor cells
A Storch et al.
JOURNAL OF CHEMICAL NEUROANATOMY (2003)
Novel functions and signalling pathways for GDNF
H Sariola et al.
JOURNAL OF CELL SCIENCE (2003)
A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease
CW Olanow et al.
ANNALS OF NEUROLOGY (2003)
Both apoptosis and necrosis occur early after intracerebral grafting of ventral mesencephalic tissue:: a role for protease activation
M Emgård et al.
JOURNAL OF NEUROCHEMISTRY (2003)
Transplantation in Parkinson's disease: PET changes correlate with the amount of grafted tissue
V Cochen et al.
MOVEMENT DISORDERS (2003)
Gene expression in human neural stem cells: effects of leukemia inhibitory factor
LS Wright et al.
JOURNAL OF NEUROCHEMISTRY (2003)
Intraputamenal infusion of GDNF in aged rhesus monkeys: Distribution and dopaminergic effects
Y Ai et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2003)
Idiopathic Parkinson's disease:: possible routes by which vulnerable neuronal types may be subject to neuroinvasion by an unknown pathogen
H Braak et al.
JOURNAL OF NEURAL TRANSMISSION (2003)
Glial cell line-derived neurotrophic factor-supplemented hibernation of fetal ventral mesencephalic neurons for transplantation in Parkinson disease: long-term storage
AO Hebb et al.
JOURNAL OF NEUROSURGERY (2003)
Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease
SS Gill et al.
NATURE MEDICINE (2003)
Staging of brain pathology related to sporadic Parkinson's disease
H Braak et al.
NEUROBIOLOGY OF AGING (2003)
Comparative study of GDNF delivery systems for the CNS:: polymer rods, encapsulated cells, and lentiviral vectors
JC Bensadoun et al.
JOURNAL OF CONTROLLED RELEASE (2003)
Randomized, double-blind trial of glial cell line-derived neurotrophic factor (GDNF) in PD
JG Nutt et al.
NEUROLOGY (2003)
Designing neuroprotection trials in Parkinson's disease
K Kieburtz
ANNALS OF NEUROLOGY (2003)
In vivo gene delivery of glial cell line-derived neurotrophic factor for Parkinson's disease
JH Kordower
ANNALS OF NEUROLOGY (2003)
Neural stem cells display an inherent mechanism for rescuing dysfunctional neurons
J Ourednik et al.
NATURE BIOTECHNOLOGY (2002)
Dyskinesia after fetal cell transplantation for parkinsonism: A PET study
YL Ma et al.
ANNALS OF NEUROLOGY (2002)
Subthalamic GAD gene therapy in a Parkinson's disease rat model
J Luo et al.
SCIENCE (2002)
Chronic, controlled GDNF infusion promotes structural and functional recovery in advanced parkinsonian monkeys
R Grondin et al.
BRAIN (2002)
Aberrant sprouting and downregulation of tyrosine hydroxylase in lesioned nigrostriatal dopamine neurons induced by long-lasting overexpression of glial cell line derived neurotrophic factor in the striatum by lentiviral gene transfer
B Georgievska et al.
EXPERIMENTAL NEUROLOGY (2002)
Neurospheres modified to produce glial cell line-derived neurotrophic factor increase the survival of transplanted dopamine neurons
T Ostenfeld et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2002)
Effects of chronic intraputamenal infusion of glial cell line-derived neurotrophic factor (GDNF) in aged Rhesus monkeys
N Maswood et al.
NEUROBIOLOGY OF AGING (2002)
Gene transfer of a chimeric trans-activator is immunogenic and results in short-lived transgene expression
M Latta-Mahieu et al.
HUMAN GENE THERAPY (2002)
α-Synucleinopathy and selective dopaminergic neuron loss in a rat lentiviral-based model of Parkinson's disease
C Lo Bianco et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease
JH Kim et al.
NATURE (2002)
The controlled conversion of human neural progenitor cells derived from foetal ventral mesencephalon into dopaminergic neurons in vitro
SS Riaz et al.
DEVELOPMENTAL BRAIN RESEARCH (2002)
Global gene and cell replacement strategies via stem cells
KI Park et al.
GENE THERAPY (2002)
The GDNF family: Signalling, biological functions and therapeutic value
MS Airaksinen et al.
NATURE REVIEWS NEUROSCIENCE (2002)
Reversal of motor impairments in parkinsonian rats by continuous intrastriatal delivery of L-dopa using rAAV-mediated gene transfer
D Kirik et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Regional specification of rodent and human neurospheres
T Ostenfeld et al.
DEVELOPMENTAL BRAIN RESEARCH (2002)
Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model
LM Björklund et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Behavioral recovery in a primate model of Parkinson's disease by triple transduction of striatal cells with adeno-associated viral vectors expressing dopamine-synthesizing enzymes
SI Muramatsu et al.
HUMAN GENE THERAPY (2002)
Embryonic ventral mesencephalic grafts to the substantia nigra of MPTP-treated monkeys: Feasibility relevant to multiple-target grafting as a therapy for Parkinson's disease
TJ Collier et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2002)
Neuroprotection in the rat Parkinson model by intrastriatal GDNF gene transfer using a lentiviral vector
B Georgievska et al.
NEUROREPORT (2002)
Delayed delivery of AAV-GDNF prevents nigral neurodegeneration and promotes functional recovery in a rat model of Parkinson's disease
L Wang et al.
GENE THERAPY (2002)
Characterisation of cell damage and death in embryonic mesencephalic tissue: A study on ultrastructure, vital stains and protease activity
M Emgard et al.
NEUROSCIENCE (2002)
Simultaneous intrastriatal and intranigral fetal dopaminergic grafts in patients with Parkinson disease: a pilot study - Report of three cases
I Mendez et al.
JOURNAL OF NEUROSURGERY (2002)
In vitro differentiation of transplantable neural precursors from human embryonic stem cells
SC Zhang et al.
NATURE BIOTECHNOLOGY (2001)
Neural progenitors from human embryonic stem cells
BE Reubinoff et al.
NATURE BIOTECHNOLOGY (2001)
Induced neuronal differentiation of human embryonic stem cells
M Schuldiner et al.
BRAIN RESEARCH (2001)
Segregation of human neural stem cells in the developing primate forebrain
V Ourednik et al.
SCIENCE (2001)
In vitro generation and transplantation of precursor-derived human dopamine neurons
R Sánchez-Pernaute et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2001)
Long-term proliferation and dopaminergic differentiation of human mesencephalic neural precursor cells
A Storch et al.
EXPERIMENTAL NEUROLOGY (2001)
Blinded positron emission tomography study of dopamine cell implantation for Parkinson's disease
T Nakamura et al.
ANNALS OF NEUROLOGY (2001)
Visualization, direct isolation, and transplantation of midbrain dopaminergic neurons
K Sawamoto et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Cell culture - Progenitor cells from human brain after death
TD Palmer et al.
NATURE (2001)
Transplantation of embryonic dopamine neurons for severe Parkinson's disease.
CR Freed et al.
NEW ENGLAND JOURNAL OF MEDICINE (2001)
Quantitative analysis of transgene protein, mRNA, and vector DNA following injection of an adenoviral vector harboring glial cell line-derived neurotrophic factor into the primate caudate nucleus
DA Kozlowski et al.
MOLECULAR THERAPY (2001)
Towards a neuroprotective gene therapy for Parkinson's disease:: use of adenovirus, AAV and lentivirus vectors for gene transfer of GDNF to the nigrostriatal system in the rat Parkinson model
A Björklund et al.
BRAIN RESEARCH (2000)
Delivery of a GDNF gene into the substantia nigra after a progressive 6-OHDA lesion maintains functional nigrostriatal connections
DA Kozlowski et al.
EXPERIMENTAL NEUROLOGY (2000)
Preservation of a functional nigrostriatal dopamine pathway by GDNF in the intrastriatal 6-OHDA lesion model depends on the site of administration of the trophic factor
D Kirik et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2000)
Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease
JH Kordower et al.
SCIENCE (2000)
Bilateral caudate and putamen grafts of embryonic mesencephalic tissue treated with lazaroids in Parkinson's disease
P Brundin et al.
BRAIN (2000)
Lentiviral vectors as a gene delivery system in the mouse midbrain:: Cellular and behavioral improvements in a 6-OHDA model of Parkinson's disease using GDNF
JC Bensadoun et al.
EXPERIMENTAL NEUROLOGY (2000)
Human neural precursor cells express low levels of telomerase in vitro and show diminishing cell proliferation with extensive axonal outgrowth following transplantation
T Ostenfeld et al.
EXPERIMENTAL NEUROLOGY (2000)
Mesencephalic neural stem (progenitor) cells develop to dopaminergic neurons more strongly in dopamine-depleted striatum than in intact striatum
H Nishino et al.
EXPERIMENTAL NEUROLOGY (2000)
Convection-enhanced delivery of AAV vector in parkinsonian monkeys;: In vivo detection of gene expression and restoration of dopaminergic function using pro-drug approach
KS Bankiewicz et al.
EXPERIMENTAL NEUROLOGY (2000)
Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells
SH Lee et al.
NATURE BIOTECHNOLOGY (2000)
Enhancement of survival of stored dopaminergic cells and promotion of graft survival by exposure of human fetal nigral tissue to glial cell line-derived neurotrophic factor in patients with Parkinson's disease - Report of two cases and technical considerations
I Mendez et al.
JOURNAL OF NEUROSURGERY (2000)
In vivo protection of nigral dopamine neurons by lentiviral gene transfer of the novel GDNF-family member neublastin/artemin
C Rosenblad et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2000)
Self-inactivating lentiviral vectors with enhanced transgene expression as potential gene transfer system in Parkinson's disease
N Deglon et al.
HUMAN GENE THERAPY (2000)